Cyclopiperettine, A New Amide from Piper nigrum

被引：0
作者：
Ren, Jie [1 ,2 ]
Zeng, Ting [1 ,2 ]
Ali, Zulfiqar [1 ]
Wang, Mei [1 ]
Bae, Jiyeong [1 ]
Chittiboyina, Amar G. [1 ]
Wang, Wei [2 ]
Li, Shunxiang [2 ]
Khan, Ikhlas A. [1 ,3 ]
机构：
[1] Univ Mississippi, Sch Pharm, Natl Ctr Nat Prod Res, Oxford, MS 38655 USA
[2] Hunan Univ Chinese Med, Sch Pharm, Changsha 410208, Hunan, Peoples R China
[3] Univ Mississippi, Sch Pharm, Dept Biomol Sci, Div Pharmacognosy, Oxford, MS 38655 USA
来源：
NATURAL PRODUCT COMMUNICATIONS | 2017年 / 12卷 / 12期
基金：
美国农业部;
关键词：
Piper nigrum; Essential oil; Cyclopiperettine; OIL;
D O I：
暂无
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Cyclopiperettine, a new amide, was isolated from essential oil of Piper nigrum L. together with ten known compounds, including amides, monoterpenoids, and sesquiterpenoids. The structure of cyclopiperettine was established by 1D-and 2D-NMR. and GC-MS techniques. Known compounds were identified as alpha-humulene, p-caryophyllene, caryophyllenol-II, beta-elemene, elemol, 1-terpinen-4-ol, nerolidol, pellitorine, piperolein B and piperine. The crude oil and isolated compounds exhibited no antimicrobial activity against seven microbial strains up to 20 mu g/mL.
引用
收藏
页码：1855 / 1856
页数：2
相关论文
共 18 条
  • [1] Piper species protect cardiac, hepatic and renal antioxidant status of atherogenic diet fed hamsters
    Agbor, Gabriel A.
    Akinfiresoye, Luli
    Sortino, Julianne
    Johnson, Robert
    Vinson, Joe A.
    [J]. FOOD CHEMISTRY, 2012, 134 (03) : 1354 - 1359
  • [2] Anti-inflammatory and antiarthritic effects of piperine in human interleukin 1β-stimulated fibroblast-like synoviocytes and in rat arthritis models
    Bang, Jun Soo
    Oh, Da Hee
    Choi, Hyun Mi
    Sur, Bong-Jun
    Lim, Sung-Jig
    Kim, Jung Yeon
    Yang, Hyung-In
    Yoo, Myung Chul
    Hahm, Dae-Hyun
    Kim, Kyoung Soo
    [J]. ARTHRITIS RESEARCH & THERAPY, 2009, 11 (02)
  • [3] Damanhouri Z A., 2014, Medicinal Aromatic Plants, V3, DOI DOI 10.4172/2167-0412.1000161
  • [4] New constituents from the dried fruit of Piper nigrum Linn., and their larvicidal potential against the Dengue vector mosquito Aedes aegypti
    Gulzar, Tahsin
    Uddin, Nizam
    Siddiqui, Bina Shaheen
    Naqvi, Syed N. H.
    Begum, Sabira
    Tariq, Rajput Muhammed
    [J]. PHYTOCHEMISTRY LETTERS, 2013, 6 (02) : 219 - 223
  • [5] Huang Xiangzhong, 2010, Zhongguo Zhong Yao Za Zhi, V35, P2285
  • [6] Synthesis, antimalarial, antileishmanial, and antimicrobial activities of some 8-quinolinamine analogues
    Jain, M
    Khan, SI
    Tekwani, BL
    Jacob, MR
    Singh, S
    Singh, PP
    Jain, R
    [J]. BIOORGANIC & MEDICINAL CHEMISTRY, 2005, 13 (14) : 4458 - 4466
  • [7] Liu YB, 2010, NAT PROD COMMUN, V5, P1253
  • [8] Co-administration of piperine and docetaxel results in improved anti-tumor efficacy via inhibition of CYP3A4 activity
    Makhov, Peter
    Golovine, Konstantin
    Canter, Daniel
    Kutikov, Alexander
    Simhan, Jay
    Corlew, Melany M.
    Uzzo, Robert G.
    Kolenko, Vladimir M.
    [J]. PROSTATE, 2012, 72 (06) : 661 - 667
  • [9] Piper nigrum Leaf and Stem Assisted Green Synthesis of Silver Nanoparticles and Evaluation of Its Antibacterial Activity Against Agricultural Plant Pathogens
    Paulkumar, Kanniah
    Gnanajobitha, Gnanadhas
    Vanaja, Mahendran
    Rajeshkumar, Shanmugam
    Malarkodi, Chelladurai
    Pandian, Kannaiyan
    Annadurai, Gurusamy
    [J]. SCIENTIFIC WORLD JOURNAL, 2014,
  • [10] Perry NB, 1996, FLAVOUR FRAG J, V11, P231, DOI 10.1002/(SICI)1099-1026(199607)11:4<231::AID-FFJ572>3.3.CO
12