Synthesis of 2-substituted quinazolines via iridium catalysis

被引：53
作者：
Fang, Jie [1 ]
Zhou, Jianguang [1 ]
Fang, Zhijie [2 ]
机构：
[1] Suzhou Novartis Pharma Technol Co Ltd, Chem & Analyt Dev, Changshu 215537, Jiangsu, Peoples R China
[2] Nanjing Univ Sci & Technol, Sch Chem Engn, Nanjing 210094, Jiangsu, Peoples R China
来源：
RSC ADVANCES | 2013年 / 3卷 / 02期
关键词：
ONE-POT SYNTHESIS; DIHYDROFOLATE-REDUCTASE; BREAST-CANCER; EFFICIENT; INHIBITORS; QUINOLINE; ALCOHOLS;
D O I：
10.1039/c2ra22278g
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
An iridium-catalyzed hydrogen transfer reaction was successfully applied in the synthesis of 2-substituted quinazolines in moderate yields starting from aldehydes or alcohols with 2-aminobenzylamines.
引用
收藏
页码：334 / 336
页数：3
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