The tert-butyl group in chemistry and biology

被引:70
作者
Bisel, Philippe [1 ]
Al-Momani, Loay [2 ]
Mueller, Michael [1 ]
机构
[1] Univ Freiburg, Inst Pharmaceut Sci, D-79104 Freiburg, Germany
[2] Tefila Tech Univ, Dept Chem, Tafila 66110, Jordan
关键词
D O I
10.1039/b800083b
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The unique reactivity pattern elicited by the crowded tert-butyl group is highlighted by summarising characteristic applications. Starting from the use of this simple hydrocarbon moiety in chemical transformations, via its relevance in Nature and its implication in biosynthetic and biodegradation pathways, the way through to its possible application in biocatalytic processes is described.
引用
收藏
页码:2655 / 2665
页数:11
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