Association of Metabolic Syndrome with the Adiponectin to Homeostasis Model Assessment of Insulin Resistance Ratio

被引：18

作者：

Ding, Yu-Song ^{[1
,2
]}

Guo, Shu-Xia ^{[2
,3
,4
]}

Ma, Ru-Lin ^{[2
]}

Li, Shu-Gang ^{[2
]}

Guo, Heng ^{[2
]}

Zhang, Jing-Yu ^{[2
]}

Zhang, Mei ^{[2
]}

Liu, Jia-Ming ^{[2
]}

He, Jia ^{[2
]}

Yan, Yi-zhong ^{[2
]}

Zhang, Wen-Jie ^{[3
,4
]}

Liu, Lie-Gang ^{[1
]}

机构：

[1] Huazhong Univ Sci & Technol, Tongji Med Coll, Dept Food Hyg & Nutr, Wuhan 430030, Peoples R China

[2] Shihezi Univ, Sch Med, Dept Publ Hlth, Shihezi 832000, Xinjiang, Peoples R China

[3] Shihezi Univ, Sch Med, Dept Pathol, Shihezi 832002, Xinjiang, Peoples R China

[4] Shihezi Univ, Sch Med, Minist Educ, Key Lab Xinjiang Endem & Ethn Dis, Shihezi 832002, Xinjiang, Peoples R China

来源：

MEDIATORS OF INFLAMMATION | 2015年 / 2015卷

基金：

中国国家自然科学基金;

关键词：

LOW-GRADE INFLAMMATION; LEPTIN; DISEASE; MARKER; RISK;

D O I：

10.1155/2015/607364

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

This study aimed at determining whether the adiponectin to HOMA-IR (A/H) ratio is associated with MetS and MetS components and comparing the diagnostic efficacy of adiponectin, HOMA-IR, and the A/H ratio in healthy, middle-aged participants. MetS was assessed in 1628 Kazakh participants (men, 768; women, 860). The associations between adiponectin, HOMA-IR, and the A/H ratio with the components of MetS and MetS were examined using logistic regression analysis and receiver operating characteristic (ROC) curves. Our results show that A/H ratio may be a better diagnostic marker for MetS than either HOMA-IR or adiponectin alone, and it may serve as an important biomarker to determine an increased risk for MetS in healthy middle-aged population.

引用

页数：7

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