Electrochemical Synthesis of the Aryl α-Ketoesters from Acetophenones Mediated by KI

被引：68

作者：

Zhang, Zhenlei ^{[1
,2
]}

Su, Jihu ^{[3
,4
]}

Zha, Zhenggen ^{[1
,2
]}

Wang, Zhiyong ^{[1
,2
]}

机构：

[1] Univ Sci & Technol China, CAS Key Lab Soft Matter Chem, Hefei Natl Lab Phys Sci Microscale, Hefei 230026, Anhui, Peoples R China

[2] Univ Sci & Technol China, Dept Chem, Hefei 230026, Anhui, Peoples R China

[3] Univ Sci & Technol China, Hefei Natl Lab Phys Sci Microscale, Hefei 230026, Anhui, Peoples R China

[4] Univ Sci & Technol China, Dept Modern Phys, Hefei 230026, Anhui, Peoples R China

来源：

CHEMISTRY-A EUROPEAN JOURNAL | 2013年 / 19卷 / 52期

关键词：

bond-forming reactions; electrochemistry oxidation; esterification; iodine radical; oxygen; DIRECT ALDOL REACTION; KETO-ESTERS; AEROBIC OXIDATION; MOLECULAR-OXYGEN; HYDROXY ESTERS; METHYL KETONES; ACID; EFFICIENT; ACTIVATION; ALDEHYDES;

D O I：

10.1002/chem.201302307

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Two C-O bonds formed in one step: The oxidative coupling reaction of acetophenones with alcohol was developed by a dioxygen activation to afford α-ketoesters under electrochemical conditions. This novel transformation not only provides a simple and efficient approach to synthetize α-ketoester derivatives, but also invents a new strategy to construct a C-O bond by virtue of an anode oxidation (see scheme). Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：17711 / 17714

页数：4

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