Migraine, arousal and sleep deprivation: comment on: "sleep quality, arousal and pain thresholds in migraineurs: a blinded controlled polysomnographic study"

被引：3

作者：

Vollono, Catello ^{[1
]}

Testani, Elisa ^{[1
]}

Losurdo, Anna ^{[1
]}

Mazza, Salvatore ^{[1
]}

Della Marca, Giacomo ^{[1
]}

机构：

[1] Catholic Univ, Inst Neurol, Policlin Univ A Gemelli, I-00168 Rome, Italy

来源：

JOURNAL OF HEADACHE AND PAIN | 2013年 / 14卷

关键词：

Migraine; Sleep; Sleep deprivation; Cyclic alternating pattern; Arousal; Pain;

D O I：

10.1186/1129-2377-14-50

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

We discuss the hypothesis proposed by Engstrom and coworkers that Migraineurs have a relative sleep deprivation, which lowers the pain threshold and predispose to attacks. Previous data indicate that Migraineurs have a reduction of Cyclic Alternating Pattern (CAP), an essential mechanism of NREM sleep regulation which allows to dump the effect of incoming disruptive stimuli, and to protect sleep. The modifications of CAP observed in Migraineurs are similar to those observed in patients with impaired arousal (narcolepsy) and after sleep deprivation. The impairment of this mechanism makes Migraineurs more vulnerable to stimuli triggering attacks during sleep, and represents part of a more general vulnerability to incoming stimuli.

引用

页数：2

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