The effect of quercetin on the prevention or treatment of COVID-19 and other respiratory tract infections in humans: A rapid review

被引：44

作者：

Aucoin, Monique ^{[1
]}

Cooley, Kieran ^{[1
,2
,3
]}

Saunders, Paul Richard ^{[1
]}

Cardozo, Valentina ^{[1
]}

Remy, Daniella ^{[1
]}

Cramer, Holger ^{[2
,4
]}

Abad, Carlos Neyre ^{[5
]}

Hannan, Nicole ^{[6
]}

机构：

[1] Canadian Coll Naturopath Med, Toronto, ON, Canada

[2] Univ Technol Sydney, Australian Res Ctr Complementary & Integrat Med, Sydney, NSW, Australia

[3] Pacific Coll Hlth Sci, San Diego, CA USA

[4] Univ Duisburg Essen, Fac Med, Dept Internal & Integrat Med, Kliniken Essen Mitte, Essen, Germany

[5] Univ Calif Los Angeles, Los Angeles, CA USA

[6] Griffith Univ, Sch Pharm & Pharmacol, Gold Coast, Qld, Australia

来源：

ADVANCES IN INTEGRATIVE MEDICINE | 2020年 / 7卷 / 04期

关键词：

Quercetin; Respiratory tract infection; COVID; COVID-19; Rapid review; ILLNESS;

D O I：

10.1016/j.aimed.2020.07.007

中图分类号：

R [医药、卫生];

学科分类号：

10 ;

摘要：

Brief overview: There is currently insufficient evidence to recommend quercetin supplementation as a therapy for the treatment or prevention of COVID-19. Three human clinical trials with low risk of bias suggest that oral quercetin may have a beneficial effect on the incidence and duration of respiratory tract infections in certain populations; however, further research is needed. Verdict: Current evidence on the efficacy of quercetin supplementation in the treatment and prevention of COVID-19 is insufficient for its clinical recommendation at this time. Quercetin exhibits both immunomodulatory and antimicrobial effects in preclinical studies; however, only three human clinical trials, each with a low risk of bias rating, were identified in this rapid review. One study reported a decrease in incidence of upper respiratory tract infections following a competitive athletic event. A larger community clinical trial reported a benefit in older, athletic adults only. (C) 2020 Elsevier Ltd. All rights reserved.

引用

页码：247 / 251

页数：5

共 4 条

[1] Quercetin supplementation and upper respiratory tract infection: A randomized community clinical trial [J].