Acute Demyelinating Disorders of the Central Nervous System

被引：8

作者：

Harris, Meghan K. ^{[1
]}

Maghzi, Amir Hadi ^{[1
]}

Etemadifar, Masoud ^{[1
]}

Kelley, Roger E. ^{[1
]}

Gonzalez-Toledo, Eduardo ^{[1
]}

Minagar, Alireza ^{[1
]}

机构：

[1] Louisiana State Univ, Hlth Sci Ctr, Dept Neurol, Shreveport, LA 71115 USA

来源：

CURRENT TREATMENT OPTIONS IN NEUROLOGY | 2009年 / 11卷 / 01期

关键词：

ACUTE DISSEMINATED ENCEPHALOMYELITIS; INTRAVENOUS IMMUNOGLOBULIN THERAPY; MULTIPLE-SCLEROSIS; PLASMA-EXCHANGE; IV IMMUNOGLOBULIN; RANDOMIZED-TRIAL; DOUBLE-BLIND; METHYLPREDNISOLONE; PLASMAPHERESIS; CHILDREN;

D O I：

10.1007/s11940-009-0008-6

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Opinion statement Acute demyelinating disorders of the central nervous system represent some of the most formidable management and therapeutic challenges to clinicians. These disorders include acute relapses of multiple sclerosis, neuromyelitis optica, acute disseminated encephalomyelitis, optic neuritis, and transverse myelitis. This paper summarizes clinical manifestations of these disorders, as well as treatment strategies. Currently, immunosuppression with corticosteroids for the acute events is the mainstay of treatment. Other experimental therapies, which may be effective in certain patients, are discussed.

引用

页码：55 / 63

页数：9

共 29 条

[1] Neuromyelitis optica: a distinct demyelinating disease of the central nervous system [J].

Argyriou, A. A. ;

Makris, N. .

ACTA NEUROLOGICA SCANDINAVICA, 2008, 118 (04) :209-217

[2] A RANDOMIZED, CONTROLLED TRIAL OF CORTICOSTEROIDS IN THE TREATMENT OF ACUTE OPTIC NEURITIS [J].

BECK, RW ;

CLEARY, PA ;

ANDERSON, MM ;

KELTNER, JL ;

SHULTS, WT ;

KAUFMAN, DI ;

BUCKLEY, EG ;

CORBETT, JJ ;

KUPERSMITH, MJ ;

MILLER, NR ;

SAVINO, PJ ;

GUY, JR ;

TROBE, JD ;

MCCRARY, JA ;

SMITH, CH ;

CHROUSOS, GA ;

THOMPSON, HS ;

KATZ, BJ ;

BRODSKY, MC ;

GOODWIN, JA ;

ATWELL, CW .

NEW ENGLAND JOURNAL OF MEDICINE, 1992, 326 (09) :581-588

[3] EVALUATION OF IL-2, SIL2R, IL-6, TNF-ALPHA, AND IL-1-BETA LEVELS IN SERUM AND CSF OF PATIENTS WITH OPTIC NEURITIS [J].

DECKERTSCHLUTER, M ;

SCHLUTER, D ;

SCHWENDEMANN, G .

JOURNAL OF THE NEUROLOGICAL SCIENCES, 1992, 113 (01) :50-54

[4] Efficacy of high dose steroid therapy in children with severe acute transverse myelitis [J].

Defresne, P ;

Meyer, L ;

Tardieu, M ;

Scalais, E ;

Nuttin, C ;

De Bont, B ;

Loftus, G ;

Landrieu, P ;

Kadhim, H ;

Sébire, G .

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2001, 71 (02) :272-274

[5] Intravenous immunoglobulin in relapsing-remitting multiple sclerosis - A dose-finding trial [J].

Fazekas, F. ;

Lublin, F. D. ;

Li, D. ;

Freedman, M. S. ;

Hartung, H. P. ;

Rieckmann, P. ;

Sorensen, P. Soelberg ;

Maas-Enriquez, M. ;

Sommerauer, B. ;

Hanna, K. .

NEUROLOGY, 2008, 71 (04) :265-271

[6] Guidelines on the use of intravenous immune globulin for neurologic conditions [J].

Feasby, Tom ;

Banwell, Brenda ;

Benstead, Timothy ;

Bril, Vera ;

Brouwers, Melissa ;

Freedman, Mark ;

Hahn, Angelika ;

Hume, Heather ;

Freedman, John ;

Pi, David ;

Wadsworth, Louis .

TRANSFUSION MEDICINE REVIEWS, 2007, 21 (02) :S57-S107

[7] Medical progress: Multiple sclerosis - The plaque and its pathogenesis [J].

Frohman, EM ;

Racke, MK ;

Raine, CS .

NEW ENGLAND JOURNAL OF MEDICINE, 2006, 354 (09) :942-955

[8] The relationship of MS to physical trauma and psychological stress - Report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology [J].

Goodin, DS ;

Ebers, GC ;

Johnson, KP ;

Rodriguez, M ;

Sibley, WA ;

Wolinsky, JS .

NEUROLOGY, 1999, 52 (09) :1737-1745

[9] Acute fulminant multiple sclerosis and plasma exchange [J].

Jacquerye, P ;

Ossemann, M ;

Laloux, P ;

Dive, A ;

De Coene, B .

EUROPEAN NEUROLOGY, 1999, 41 (03) :174-175

[10] Is methyl prednisolone useful in acute transverse myelitis? [J].

Kalita, J ;

Misra, UK .

SPINAL CORD, 2001, 39 (09) :471-476

← 1 2 3 →