SnapShot: Genetics of Alzheimer's Disease

被引：82

作者：

Guerreiro, Rita ^{[1
]}

Bras, Jose ^{[1
]}

Hardy, John ^{[1
]}

机构：

[1] UCL, Reta Lilla Weston Inst, London WC1N 1PJ, England

来源：

CELL | 2013年 / 155卷 / 04期

关键词：

D O I：

10.1016/j.cell.2013.10.037

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：968 / +

页数：2

共 6 条

[1] Use of next-generation sequencing and other whole-genome strategies to dissect neurological disease [J].

Bras, Jose ;

Guerreiro, Rita ;

Hardy, John .

NATURE REVIEWS NEUROSCIENCE, 2012, 13 (07) :453-464

[2] AMYLOID DEPOSITION AS THE CENTRAL EVENT IN THE ETIOLOGY OF ALZHEIMERS-DISEASE [J].

HARDY, J ;

ALLSOP, D .

TRENDS IN PHARMACOLOGICAL SCIENCES, 1991, 12 (10) :383-388

[3] Genetic Evidence Implicates the Immune System and Cholesterol Metabolism in the Aetiology of Alzheimer's Disease [J].

Jones, Lesley ;

Holmans, Peter A. ;

Hamshere, Marian L. ;

Harold, Denise ;

Moskvina, Valentina ;

Ivanov, Dobril ;

Pocklington, Andrew ;

Abraham, Richard ;

Hollingworth, Paul ;

Sims, Rebecca ;

Gerrish, Amy ;

Pahwa, Jaspreet Singh ;

Jones, Nicola ;

Stretton, Alexandra ;

Morgan, Angharad R. ;

Lovestone, Simon ;

Powell, John ;

Proitsi, Petroula ;

Lupton, Michelle K. ;

Brayne, Carol ;

Rubinsztein, David C. ;

Gill, Michael ;

Lawlor, Brian ;

Lynch, Aoibhinn ;

Morgan, Kevin ;

Brown, Kristelle S. ;

Passmore, Peter A. ;

Craig, David ;

McGuinness, Bernadette ;

Todd, Stephen ;

Holmes, Clive ;

Mann, David ;

Smith, A. David ;

Love, Seth ;

Kehoe, Patrick G. ;

Mead, Simon ;

Fox, Nick ;

Rossor, Martin ;

Collinge, John ;

Maier, Wolfgang ;

Jessen, Frank ;

Schuermann, Britta ;

van den Bussche, Hendrik ;

Heuser, Isabella ;

Peters, Oliver ;

Kornhuber, Johannes ;

Wiltfang, Jens ;

Dichgans, Martin ;

Froelich, Lutz ;

Hampel, Harald .

PLOS ONE, 2010, 5 (11)

[4] A mutation in APP protects against Alzheimer's disease and age-related cognitive decline [J].

Jonsson, Thorlakur ;

Atwal, Jasvinder K. ;

Steinberg, Stacy ;

Snaedal, Jon ;

Jonsson, Palmi V. ;

Bjornsson, Sigurbjorn ;

Stefansson, Hreinn ;

Sulem, Patrick ;

Gudbjartsson, Daniel ;

Maloney, Janice ;

Hoyte, Kwame ;

Gustafson, Amy ;

Liu, Yichin ;

Lu, Yanmei ;

Bhangale, Tushar ;

Graham, Robert R. ;

Huttenlocher, Johanna ;

Bjornsdottir, Gyda ;

Andreassen, Ole A. ;

Jonsson, Erik G. ;

Palotie, Aarno ;

Behrens, Timothy W. ;

Magnusson, Olafur T. ;

Kong, Augustine ;

Thorsteinsdottir, Unnur ;

Watts, Ryan J. ;

Stefansson, Kari .

NATURE, 2012, 488 (7409) :96-99

[5] Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease [J].

Lambert, Jean-Charles ;

Ibrahim-Verbaas, Carla A. ;

Harold, Denise ;

Naj, Adam C. ;

Sims, Rebecca ;

Bellenguez, Celine ;

Jun, Gyungah ;

DeStefano, Anita L. ;

Bis, Joshua C. ;

Beecham, Gary W. ;

Grenier-Boley, Benjamin ;

Russo, Giancarlo ;

Thornton-Wells, Tricia A. ;

Jones, Nicola ;

Smith, Albert V. ;

Chouraki, Vincent ;

Thomas, Charlene ;

Ikram, M. Arfan ;

Zelenika, Diana ;

Vardarajan, Badri N. ;

Kamatani, Yoichiro ;

Lin, Chiao-Feng ;

Gerrish, Amy ;

Schmidt, Helena ;

Kunkle, Brian ;

Dunstan, Melanie L. ;

Ruiz, Agustin ;

Bihoreau, Marie-Therese ;

Choi, Seung-Hoan ;

Reitz, Christiane ;

Pasquier, Florence ;

Hollingworth, Paul ;

Ramirez, Alfredo ;

Hanon, Olivier ;

Fitzpatrick, Annette L. ;

Buxbaum, Joseph D. ;

Campion, Dominique ;

Crane, Paul K. ;

Baldwin, Clinton ;

Becker, Tim ;

Gudnason, Vilmundur ;

Cruchaga, Carlos ;

Craig, David ;

Amin, Najaf ;

Berr, Claudine ;

Lopez, Oscar L. ;

De Jager, Philip L. ;

Deramecourt, Vincent ;

Johnston, Janet A. ;

Evans, Denis .

NATURE GENETICS, 2013, 45 (12) :1452-U206

[6] Finding the missing heritability of complex diseases [J].

Manolio, Teri A. ;

Collins, Francis S. ;

Cox, Nancy J. ;

Goldstein, David B. ;

Hindorff, Lucia A. ;

Hunter, David J. ;

McCarthy, Mark I. ;

Ramos, Erin M. ;

Cardon, Lon R. ;

Chakravarti, Aravinda ;

Cho, Judy H. ;

Guttmacher, Alan E. ;

Kong, Augustine ;

Kruglyak, Leonid ;

Mardis, Elaine ;

Rotimi, Charles N. ;

Slatkin, Montgomery ;

Valle, David ;

Whittemore, Alice S. ;

Boehnke, Michael ;

Clark, Andrew G. ;

Eichler, Evan E. ;

Gibson, Greg ;

Haines, Jonathan L. ;

Mackay, Trudy F. C. ;

McCarroll, Steven A. ;

Visscher, Peter M. .

NATURE, 2009, 461 (7265) :747-753

← 1 →