Depression and Parkinson's Disease: Current Knowledge

被引：259
作者：
Marsh, Laura [1 ,2 ]
机构：
[1] Baylor Coll Med, Dept Psychiat, Houston, TX 77030 USA
[2] Baylor Coll Med, Dept Neurol, Michael E DeBakey Vet Affairs Med Ctr, Houston, TX 77030 USA
来源：
CURRENT NEUROLOGY AND NEUROSCIENCE REPORTS | 2013年 / 13卷 / 12期
关键词：
Depression; Parkinson's disease; Mood disorder; Psychiatric; Antidepressant; Cognitive behavioral therapy; Electroconvulsive therapy; Quality of life; Treatment; Suicide; Major depression: dysthymia; Minor depression; Subsyndromal depression; Epidemiology; Pathophysiology; COGNITIVE-BEHAVIORAL THERAPY; TRANSCRANIAL MAGNETIC STIMULATION; SEROTONIN TRANSPORTER GENE; DOUBLE-BLIND; NONMOTOR SYMPTOMS; CONTROLLED-TRIAL; ANXIETY DISORDERS; ALLELIC VARIATION; FOLLOW-UP; PLACEBO;
D O I：
10.1007/s11910-013-0409-5
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Depressive disturbances are common in patients with Parkinson's disease (PD) and influence many other clinical aspects of the disease. In addition to causing inherent emotional distress, depressive disorders negatively impact quality of life, motor and cognitive deficits, functional disability, and other psychiatric comorbidities in patients with PD. Knowledge of the pathophysiology of PD depression remains limited. However, clinical studies demonstrate the efficacy of medications and psychotherapies for PD depression, underscoring the importance of their timely detection and concerted management.
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页数：9
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