Diagnosis, Development, and Treatment of Portal Vein Thrombosis in Patients With and Without Cirrhosis

被引：287
作者：
Intagliata, Nicolas M. [1 ]
Caldwell, Stephen H. [1 ]
Tripodi, Armando [2 ,3 ]
机构：
[1] Univ Virginia, Div Gastroenterol & Hepatol, Med Ctr, POB 800708, Charlottesville, VA 22908 USA
[2] Fdn Ist Ricovero & Cura Carattere Sci Ca Granda O, Angelo Bianchi Bon Hemophilia & Thrombosis Ctr, Milan, Italy
[3] Fdn Luigi Villa, Milan, Italy
来源：
GASTROENTEROLOGY | 2019年 / 156卷 / 06期
关键词：
Hepatic; Therapy; Fibrosis; Anticoagulation; INTRAHEPATIC PORTOSYSTEMIC SHUNT; MOLECULAR-WEIGHT HEPARIN; MESENTERIC VENOUS THROMBOSIS; DIRECT ORAL ANTICOAGULANTS; BUDD-CHIARI-SYNDROME; ED AMERICAN-COLLEGE; LIVER-TRANSPLANTATION; RISK-FACTORS; CAVERNOUS TRANSFORMATION; ANTITHROMBOTIC THERAPY;
D O I：
10.1053/j.gastro.2019.01.265
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
Portal vein thrombosis unrelated to solid malignancy is common in patients with cirrhosis, but less frequently observed in patients without cirrhosis. Prompt diagnosis and management of acute symptomatic portal vein thrombosis are essential. Failure to detect and treat thromboses can result in mesenteric ischemia, chronic cavernous transformation, and complications of portal hypertension. In patients with cirrhosis, development of portal vein thrombosis is often insidious and remains undetected until its incidental detection. Management of portal vein thrombosis in patients with cirrhosis is more controversial. However, there are data to support treatment of specific patients with anticoagulation agents. We review the common and distinct features of portal vein thromboses in patients without liver tumors, with and without cirrhosis.
引用
收藏
页码：1582 / +
页数：19
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