Successful treatment of syringotropic CD8+mycosis fungoides accompanied by hypohidrosis with vorinostat and retinoids

被引:7
作者
Kakizaki, Aya [1 ]
Fujimura, Taku [1 ]
Mizuashi, Masato [1 ]
Watabe, Akiko [1 ]
Kambayashi, Yumi [1 ]
Aiba, Setsuya [1 ]
机构
[1] Tohoku Univ, Grad Sch Med, Dept Dermatol, Sendai, Miyagi 980, Japan
基金
日本学术振兴会;
关键词
CD8<bold>+</bold>MF; hypohidrosis; syringotropism; vorinostat; MYCOSIS-FUNGOIDES;
D O I
10.1111/j.1440-0960.2012.00944.x
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
We describe a 34-year-old Japanese man with syringotropic CD8+ mycosis fungoides (MF) accompanied by hypohidrosis who was treated with vorinostat and retinoids. Interestingly, immunohistochemical staining for dermcidin revealed a decrease of sweat in the eccrine glands, and a sweat test by the iodine starch method proved hypohidrosis in the MF-affected areas. Six months after treatment with this combination therapy, the patient's advanced MF was under control.
引用
收藏
页码:E82 / E84
页数:3
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