15 years of progress in gestational trophoblastic disease: Scoring, standardization, and salvage

被引:81
作者
Brown, Jubilee [1 ]
Naumann, R. Wendel [1 ]
Seckl, Michael J. [2 ]
Schink, Julian [3 ,4 ]
机构
[1] Carolinas HealthCare Syst, Levine Canc Inst, Charlotte, NC USA
[2] Imperial Coll London, Dept Med Oncol, Charing Cross Trophoblast Dis Ctr, Charing Cross Campus, London, England
[3] Dept Obstet, Spectrum Hlth Med Grp, Gynecol, Grand Rapids, MI USA
[4] Womens Hlth Grp, Grand Rapids, MI USA
关键词
Gestational trophoblastic disease; Choriocarcinoma; Placental site trophoblastic tumor; Hydatidiform mole; INTERNATIONAL-SOCIETY; CURRENT MANAGEMENT; HYDATIDIFORM MOLE; ACTINOMYCIN-D; RISK; NEOPLASIA; TUMORS; PREGNANCY; DIAGNOSIS; METHOTREXATE;
D O I
10.1016/j.ygyno.2016.08.330
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Significant improvements in treatment and the understanding of gestational trophoblastic neoplasia have occurred in the last 15 years. These diseases are almost always curable, and refractory patients have more options for salvage therapy. Recent improvements in the understanding of epidemiology, diagnosis, and cell biology have resulted in changes in staging, advances in treatment options, and opportunities for fertility preservation. (C) 2016 Published by Elsevier Inc.
引用
收藏
页码:200 / 207
页数:8
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