Direct SARS-CoV-2 infection of the heart potentiates the cardiovascular sequelae of COVID-19

被引：14
作者：
Bose, Rajendran J. C. [1 ]
McCarthy, Jason R. [1 ]
机构：
[1] Masonic Med Res Inst, 2150 Bleecker St, Utica, NY 13501 USA
来源：
DRUG DISCOVERY TODAY | 2020年 / 25卷 / 09期
关键词：
SARS; ACE2;
D O I：
10.1016/j.drudis.2020.06.021
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
引用
收藏
页码：1559 / 1560
页数：2
相关论文
共 10 条
  • [1] Genomic characterization of the 2019 novel human-pathogenic coronavirus isolated from a patient with atypical pneumonia after visiting Wuhan
    Chan, Jasper Fuk-Woo
    Kok, Kin-Hang
    Zhu, Zheng
    Chu, Hin
    To, Kelvin Kai-Wang
    Yuan, Shuofeng
    Yuen, Kwok-Yung
    [J]. EMERGING MICROBES & INFECTIONS, 2020, 9 (01) : 221 - 236
  • [2] From SARS to MERS: crystallographic studies on coronaviral proteases enable antiviral drug design
    Hilgenfeld, Rolf
    [J]. FEBS JOURNAL, 2014, 281 (18) : 4085 - 4096
  • [3] SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
    Hoffmann, Markus
    Kleine-Weber, Hannah
    Schroeder, Simon
    Krueger, Nadine
    Herrler, Tanja
    Erichsen, Sandra
    Schiergens, Tobias S.
    Herrler, Georg
    Wu, Nai-Huei
    Nitsche, Andreas
    Mueller, Marcel A.
    Drosten, Christian
    Poehlmann, Stefan
    [J]. CELL, 2020, 181 (02) : 271 - +
  • [4] Structure of Mpro from SARS-CoV-2 and discovery of its inhibitors
    Jin, Zhenming
    Du, Xiaoyu
    Xu, Yechun
    Deng, Yongqiang
    Liu, Meiqin
    Zhao, Yao
    Zhang, Bing
    Li, Xiaofeng
    Zhang, Leike
    Peng, Chao
    Duan, Yinkai
    Yu, Jing
    Wang, Lin
    Yang, Kailin
    Liu, Fengjiang
    Jiang, Rendi
    Yang, Xinglou
    You, Tian
    Liu, Xiaoce
    Yang, Xiuna
    Bai, Fang
    Liu, Hong
    Liu, Xiang
    Guddat, Luke W.
    Xu, Wenqing
    Xiao, Gengfu
    Qin, Chengfeng
    Shi, Zhengli
    Jiang, Hualiang
    Rao, Zihe
    Yang, Haitao
    [J]. NATURE, 2020, 582 (7811) : 289 - +
  • [5] SARS-associated coronavirus replication in cell lines
    Kaye, M
    Druce, J
    Tran, T
    Kostecki, R
    Chibo, D
    Morris, J
    Catton, M
    Birch, C
    [J]. EMERGING INFECTIOUS DISEASES, 2006, 12 (01) : 128 - 133
  • [6] Potential Effects of Coronaviruses on the Cardiovascular System A Review
    Madjid, Mohammad
    Safavi-Naeini, Payam
    Solomon, Scott D.
    Vardeny, Orly
    [J]. JAMA CARDIOLOGY, 2020, 5 (07) : 831 - 840
  • [7] Muus C, 2020, BIORXIV, DOI [10.1101/2020.04.19.049254, DOI 10.1101/2020.04.19.049254]
  • [8] SARS-coronavirus modulation of myocardial ACE2 expression and inflammation in patients with SARS
    Oudit, G. Y.
    Kassiri, Z.
    Jiang, C.
    Liu, P. P.
    Poutanen, S. M.
    Penninger, J. M.
    Butany, J.
    [J]. EUROPEAN JOURNAL OF CLINICAL INVESTIGATION, 2009, 39 (07) : 618 - 625
  • [9] Sharma A., 2020, BIORXIV
  • [10] Tucker NR, 2020, MYOCYTE SPECIFIC UPR
1