Lycopodium Alkaloids: Isolation and Asymmetric Synthesis

被引：99
作者：
Kitajima, Mariko [1 ]
Takayama, Hiromitsu [1 ]
机构：
[1] Chiba Univ, Grad Sch Pharmaceut Sci, Inage Ku, Chiba 2638522, Japan
来源：
ALKALOID SYNTHESIS | 2012年 / 309卷
关键词：
Alkaloid; Asymmetric synthesis; Isolation; Lycopodium; Structure elucidation; ALPHA-AMINATION; SERRATUM THUNB; HOMOALLYLIC ALCOHOLS; SAMARIUM(II) IODIDE; CERNUANE-TYPE; HUPERZINE-A; SERRATININE; ALDEHYDES; (+)-COMPLANADINE; CONFIGURATION;
D O I：
10.1007/128_2011_126
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Lycopodium alkaloids have attracted the attention of many natural product chemists and synthetic organic chemists due to their important biological activities and unique skeletal characteristics. In this review we describe isolation and asymmetric syntheses of several new alkaloids such as lycoposerramines-C, -V, -W, and cernuine, and show that asymmetric total synthesis played a key role in elucidating the structures of these complex natural products.
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页码：1 / 31
页数：31
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