Natural and edible biopolymer poly-γ-glutamic acid:: Synthesis, production, and applications

被引：208

作者：

Sung, MH

Park, C

Kim, CJ

Poo, H

Soda, K

Ashiuchi, M

机构：

[1] Kookmin Univ, Dept Bio & Nanochem, Seoul 136702, South Korea

[2] BioLeaders Corp, Taejon 305500, South Korea

[3] Chungnam Natl Univ, Dept Vet Med, Taejon 305764, South Korea

[4] Korea Res Inst Biosci & Biotechnol, Syst Proteom Res Ctr, Taejon 305333, South Korea

[5] BioLeaders Japan Corp, Ibaraki, Osaka, Japan

[6] Kochi Univ, Dept Bioresources Sci, Nankoku, Kochi 7838502, Japan

来源：

CHEMICAL RECORD | 2005年 / 5卷 / 06期

关键词：

Bacillus subtilis (chungkookjang); poly-gamma-glutamic acid; high molecular weight; immune-stimulating agent; anti-tumor agent;

D O I：

10.1002/tcr.20061

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Poly-gamma-glutamic acid (gamma-PGA) is a very promising biodegradable polymer that is produced by Bacillus subtilis. gamma-PGA is water-soluble, anionic, biodegradable, and edible. This paper reviews the production of a strain of gamma-PGA and recent developments with respect to applications in terms of Ca absorption, moisturizing properties, gamma-PGA conjugation, super absorbent polymer, and so on. Our recent research shows that gamma-PGA can be used as an immune-stimulating and anti-tumor agent, especially at high molecular weight. (c) 2005 The Japan Chemical Journal Forum and Wiley Periodicals, Inc.

引用

页码：352 / 366

页数：15

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