Origins and functions of the chlamydial inclusion

被引:163
作者
Hackstadt, T [1 ]
Fischer, ER [1 ]
Scidmore, MA [1 ]
Rockey, DD [1 ]
Heinzen, RA [1 ]
机构
[1] NIAID,MICROSCOPY BRANCH,NIH,ROCKY MT LABS,HAMILTON,MT 59840
关键词
D O I
10.1016/S0966-842X(97)01061-5
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Chlamydiae dissociate themselves from the endocytic pathway shortly after internalization by actively modifying the vacuole to become fusogenic with sphingomyelin-containing exocytic vesicles. Interaction with this secretory pathway appears to provide a pathogenic mechanism that allows chlamydiae to establish themselves in a site that is not destined to fuse with lysosomes.
引用
收藏
页码:288 / 293
页数:6
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