ELASTASE, MYELOPEROXIDASE, AND ALKALINE PHOSPHATASE RELEASE AND FREE RADICAL GENERATION IN NEUTROPHILS ISOLATED FROM BLOOD OF SOWS AT DIFFERENT STAGES OF OESTROUS CYCLE

被引：1
作者：
Wessely-Szponder, Joanna [1 ]
Bobowiec, Ryszard [1 ]
机构：
[1] Univ Life Sci, Fac Vet Med, Dept Pathophysiol, Chair Preclin Vet Sci, PL-20033 Lublin, Poland
来源：
BULLETIN OF THE VETERINARY INSTITUTE IN PULAWY | 2013年 / 57卷 / 01期
关键词：
sow; oestrous cycle; neutrophils; enzymes; POLYMORPHONUCLEAR LEUKOCYTES; FUNCTIONAL-CAPACITY; STEROID-HORMONES; NITRIC-OXIDE; PROGESTERONE; ESTRADIOL; SUPEROXIDE; INCREASE; CELLS;
D O I：
10.2478/bvip-2013-0012
中图分类号：
S85 [动物医学（兽医学）];
学科分类号：
0906 ;
摘要：
The aim of the study was to assess the influence of the oestrous cycle phase on neutrophil secretory activity and to extrapolate it to susceptibility to uterine infections. The obtained results indicate that the highest enzyme release seen in the late follicular phase (elastase release was 42.18 +/- 3.11% of maximal release, myeloperoxidase was 45.0 +/- 5.12%, and alkaline phosphatase was 44.75 +/- 9.0%) was related to the level of 17 beta-oestradiol in plasma. Similarly, a free radical generation was also the most enhanced during this phase. Significantly lower values were obtained from sows during the luteal phase in regard to both enzyme release (36.62 +/- 3.58% for elastase, 27.87 +/- 8.7% for myeloperoxidase, and 22.12 +/- 2.4% for alkaline phosphatase), and that of free radicals (2.28 +/- 1.6 mu M/10(6) cells for nitric oxide and 2.47 +/- 0.6 nM/10(6) cells for superoxide).
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页码：65 / 68
页数：4
相关论文
共 21 条
  • [1] In vitro effects of different steroid hormones on superoxide anion production of human neutrophil granulocytes
    Békési, G
    Kakucs, R
    Várbíró, S
    Rácz, K
    Sprintz, D
    Fehér, J
    Székács, B
    [J]. STEROIDS, 2000, 65 (12) : 889 - 894
  • [2] Sex differences and estrogen modulation of the cellular immune response after injury
    Bird, Melanie D.
    Karavitis, John
    Kovacs, Elizabeth J.
    [J]. CELLULAR IMMUNOLOGY, 2008, 252 (1-2) : 57 - 67
  • [3] Leukocyte networks and ovulation
    Brännström, M
    Enskog, A
    [J]. JOURNAL OF REPRODUCTIVE IMMUNOLOGY, 2002, 57 (1-2) : 47 - 60
  • [4] The use of plasma progesterone profiles to predict the reproductive status of anestrous gilts and sows
    Chung, WB
    Cheng, WF
    Wu, LS
    Yang, PC
    [J]. THERIOGENOLOGY, 2002, 58 (06) : 1165 - 1174
  • [5] The relationship between the blood progesterone concentration at early metoestrus and uterine infection in the sow
    deWinter, PJJ
    Verdonck, M
    deKruif, A
    Coryn, M
    Deluyker, HA
    Devriese, LA
    Haesebrouck, F
    [J]. ANIMAL REPRODUCTION SCIENCE, 1996, 41 (01) : 51 - 59
  • [6] 17 beta-estradiol-stimulated nitric oxide production by neutrophils:: Effect on platelet activation
    Durán, MG
    Gálvez, GG
    De Frutos, T
    Recaséns, JD
    Casado, S
    Farré, AL
    [J]. OBSTETRICS AND GYNECOLOGY, 2000, 95 (02) : 284 - 290
  • [7] NEUTROPHIL ALKALINE-PHOSPHATASE ACTIVITY INCREASE IN BACTERIAL-INFECTIONS IS NOT ASSOCIATED WITH A GENERAL INCREASE IN SECRETORY VESICLE MEMBRANE-COMPONENTS
    KARLSSON, A
    KHALFAN, L
    DAHLGREN, C
    STIGBRAND, T
    FOLLIN, P
    [J]. INFECTION AND IMMUNITY, 1995, 63 (03) : 911 - 916
  • [8] Changes in the level of endogenous leptin, FSH, 17β-oestradiol and metabolites during lupin-induced increase in ovulation rate in ewes
    Kosior-Korzecka, U
    Bobowiec, R
    [J]. JOURNAL OF VETERINARY MEDICINE SERIES A-PHYSIOLOGY PATHOLOGY CLINICAL MEDICINE, 2003, 50 (07): : 343 - 349
  • [9] Kowalik Magdalena K., 2008, Medycyna Weterynaryjna, V64, P528
  • [10] Lewis G.S., 2003, REPROD BIOL ENDOCRIN
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