Hydroalcoholic extracts of Vellozia squamata: study of its nanoemulsions for pharmaceutical or cosmetic applications

被引:37
作者
Quintao, Frederico J. O. [1 ]
Tavares, Renata S. N. [1 ]
Vieira-Filho, Sidney A. [1 ]
Souza, Gustavo H. B. [1 ]
Santos, Orlando D. H. [1 ]
机构
[1] Univ Fed Ouro Preto, Dept Farm, BR-35400000 Ouro Preto, MG, Brazil
来源
REVISTA BRASILEIRA DE FARMACOGNOSIA-BRAZILIAN JOURNAL OF PHARMACOGNOSY | 2013年 / 23卷 / 01期
关键词
Vellozia squamata; Velloziaceae; DPPH; nanoemulsion formulation; nanoemulsion characterization; ANTIOXIDANT ACTIVITY; PHENOLIC-COMPOUNDS; OIL; STABILITY; EMULSIONS;
D O I
10.1590/S0102-695X2013005000001
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Some species of plants are notable for the wide range of biologically active constituents in their tissues. Chemical and pharmacological studies of Vellozia squamata Pohl, Velloziaceae, popularly known in Brasil as "canela-de-ema" are scarce, but showed the presence of di-and triterpenoid that may be of scientific interest. In the present study the hydroalcoholic extracts from leafs and stems of V. squamata were submitted to phytochemical prospection to identify the principal groups of constituents, and the antioxidant activity was determined by DPPH method. The hydroethanolic extracts presented higher antioxidant activity. Thus, nanoemulsion formulations were prepared using the method of phase inversion. Accelerated stability tests, such as heat stress and centrifugation were made, and physical and chemical properties of the nanoemulsions were established. Stable formulations were obtained from both extracts from leafs and stems. By the results was possible to establish the potential application of hydroalcoholic extracts from V. squamata in development of products with antioxidant properties and demonstrate a promising pharmaceutical product.
引用
收藏
页码:101 / 107
页数:7
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