Gastritis and gastric atrophy

被引:33
作者
El-Zimaity, Hala [1 ,2 ]
机构
[1] McMaster Univ, Dept Pathol, Hamilton, ON, Canada
[2] Baylor Coll Med, Dept Med, Michael E DeBakey Vet Affairs Med Ctr, Houston, TX 77030 USA
关键词
atrophy; gastritis; staging;
D O I
10.1097/MOG.0b013e328311d1cc
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Purpose of review The majority of problems in interpreting gastritis remain Helicobacter related, but their nature has changed. The present review covers gastritis historically through cancer risk staging systems. Recent findings Key points to remember are: Helicobacter is associated with several forms of gastritis; in the present review, I am focusing on the two ends of the disease, Helicobacter pylori infection', that starts with antral predominant gastritis but can continue to oxyntic predominant disease with atrophy; the role Helicobacter pylori plays in autoimmune gastritis with pernicious anemia remains unresolved; gastritis staging systems for cancer risk, namely Baylor and Operative Link on Gastritis Assessment, are currently available. Summary As most gastric carcinomas arise on a background of atrophic gastritis, and the risk increases with the extent of atrophy, an index of atrophy location and extent could be useful in predicting patients at greatest risk for carcinoma. It is now possible to stage patients for cancer risk. Nonetheless, in a field such as gastritis in which many issues remain unresolved, a classification or staging system that is more descriptive will likely prove more useful.
引用
收藏
页码:682 / 686
页数:5
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