Unprecedented reactivity pattern of chromium Fischer carbene complexes. Direct application to one-pot synthesis of 4-aryl-3,4-dihydrocoumarins on a multigram scale

被引：38

作者：

Barluenga, Jose ^{[1
]}

Andina, Facundo ^{[1
]}

Aznar, Fernando ^{[1
]}

机构：

[1] Univ Oviedo, Unidad Asociada CSIC, Inst Univ Quim Organomet Enrique Moles, E-33071 Oviedo, Spain

来源：

ORGANIC LETTERS | 2006年 / 8卷 / 13期

关键词：

D O I：

10.1021/ol060702e

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Reaction of alkenyl carbene chromium(0) complexes and ketene acetals triggers the formation of 4-aryl-3,4-dihydrocoumarins. The reaction can be carried out as a simple one-pot protocol in air atmosphere. The huge interest of dihydrocoumarins has prompted us to optimize a multigram-scale process.

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页码：2703 / 2706

页数：4

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