Molecular characterization of a shiga toxigenic Escherichia coli O113:H21 strain lacking eae responsible for a cluster of cases of hemolytic-uremic syndrome

被引：245

作者：

Paton, AW

Woodrow, MC

Doyle, RM

Lanser, JA

Paton, JC ^{[1
]}

机构：

[1] Womens & Childrens Hosp, Mol Microbiol Unit, Adelaide, SA 5006, Australia

[2] Inst Med & Vet Sci, Div Clin Microbiol, Adelaide, SA 5000, Australia

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 1999年 / 37卷 / 10期

关键词：

D O I：

10.1128/JCM.37.10.3357-3361.1999

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Shiga toxigenic Escherichia coli (STEC) strains are a diverse group of organisms capable of causing severe gastrointestinal disease in humans. Within the STEC family, certain strains appear to have greater virulence for humans. STEC strains carrying eae and belonging to serogroup O157 or O111 have been responsible for the vast majority of outbreaks of STEC disease reported to date. Here we describe a STEC O113:H21 strain lacking eae that was responsible for a cluster of three cases of hemolytic-uremic syndrome. This strain produces a single Stx2-related toxin and adheres efficiently to Henle 407 cells.

引用

页码：3357 / 3361

页数：5

共 33 条

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