Molecular characterization of a shiga toxigenic Escherichia coli O113:H21 strain lacking eae responsible for a cluster of cases of hemolytic-uremic syndrome

被引：245
作者：
Paton, AW
Woodrow, MC
Doyle, RM
Lanser, JA
Paton, JC [1 ]
机构：
[1] Womens & Childrens Hosp, Mol Microbiol Unit, Adelaide, SA 5006, Australia
[2] Inst Med & Vet Sci, Div Clin Microbiol, Adelaide, SA 5000, Australia
来源：
JOURNAL OF CLINICAL MICROBIOLOGY | 1999年 / 37卷 / 10期
关键词：
D O I：
10.1128/JCM.37.10.3357-3361.1999
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Shiga toxigenic Escherichia coli (STEC) strains are a diverse group of organisms capable of causing severe gastrointestinal disease in humans. Within the STEC family, certain strains appear to have greater virulence for humans. STEC strains carrying eae and belonging to serogroup O157 or O111 have been responsible for the vast majority of outbreaks of STEC disease reported to date. Here we describe a STEC O113:H21 strain lacking eae that was responsible for a cluster of three cases of hemolytic-uremic syndrome. This strain produces a single Stx2-related toxin and adheres efficiently to Henle 407 cells.
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页码：3357 / 3361
页数：5
相关论文
共 33 条
  • [1] Shiga-like toxin-producing Escherichia coli O111 and associated hemolytic-uremic syndrome: A family outbreak
    Banatvala, N
    Debeukelaer, MM
    Griffin, PM
    Barrett, TJ
    Greene, KD
    Green, JH
    Wells, JG
    [J]. PEDIATRIC INFECTIOUS DISEASE JOURNAL, 1996, 15 (11) : 1008 - 1011
  • [2] VIRULENCE FACTORS IN SHIGA-LIKE TOXIN PRODUCING ESCHERICHIA-COLI ISOLATED FROM HUMANS AND CATTLE
    BARRETT, TJ
    KAPER, JB
    JERSE, AE
    WACHSMUTH, IK
    [J]. JOURNAL OF INFECTIOUS DISEASES, 1992, 165 (05) : 979 - 980
  • [3] INDIRECT HEMAGGLUTINATION ASSAY FOR DIAGNOSIS OF ESCHERICHIA-COLI O157 INFECTION IN PATIENTS WITH HEMOLYTIC-UREMIC SYNDROME
    BITZAN, M
    KARCH, H
    [J]. JOURNAL OF CLINICAL MICROBIOLOGY, 1992, 30 (05) : 1174 - 1178
  • [4] Possible person-to-person transmission of Escherichia coli O111 - Associated hemolytic uremic syndrome
    Boudailliez, B
    Berquin, P
    MarianiKurkdjian, P
    Ilef, DD
    Cuvelier, B
    Capek, I
    Tribout, B
    Bingen, E
    Piussan, C
    [J]. PEDIATRIC NEPHROLOGY, 1997, 11 (01) : 36 - 39
  • [5] COMMUNITY-WIDE OUTBREAK OF HEMOLYTIC-UREMIC SYNDROME-ASSOCIATED WITH NON-O157 VEROCYTOTOXIN-PRODUCING ESCHERICHIA-COLI
    CAPRIOLI, A
    LUZZI, I
    ROSMINI, F
    RESTI, C
    EDEFONTI, A
    PERFUMO, F
    FARINA, C
    GOGLIO, A
    GIANVITI, A
    RIZZONI, G
    [J]. JOURNAL OF INFECTIOUS DISEASES, 1994, 169 (01): : 208 - 211
  • [6] Centers for Disease Control and Prevention (CDC), 1995, MMWR Morb Mortal Wkly Rep, V44, P501
  • [7] DISTINCT BINDING-PROPERTIES OF EAEA-NEGATIVE VEROCYTOTOXIN-PRODUCING ESCHERICHIA-COLI OF SEROTYPE O113-H21
    DYTOC, MT
    ISMAILI, A
    PHILPOTT, DJ
    SONI, R
    BRUNTON, JL
    SHERMAN, PM
    [J]. INFECTION AND IMMUNITY, 1994, 62 (08) : 3494 - 3505
  • [8] Griffin Patricia M., 1995, P739
  • [9] CLONING AND NUCLEOTIDE SEQUENCING OF VERO TOXIN 2 VARIANT GENES FROM ESCHERICHIA-COLI O91-H21 ISOLATED FROM A PATIENT WITH THE HEMOLYTIC UREMIC SYNDROME
    ITO, H
    TERAI, A
    KURAZONO, H
    TAKEDA, Y
    NISHIBUCHI, M
    [J]. MICROBIAL PATHOGENESIS, 1990, 8 (01) : 47 - 60
  • [10] JACKSON MP, 1987, FEMS MICROBIOL LETT, V44, P109, DOI 10.1111/j.1574-6968.1987.tb02252.x
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