Alloantibodies in simultaneous liver-kidney transplantation

被引：2
|
作者：
Singer, Andrew L. [1 ]
Segev, Dorry L. [2 ]
机构：
[1] Johns Hopkins Med Inst, Dept Surg, Baltimore, MD 21205 USA
[2] Johns Hopkins Med Inst, Dept Epidemiol, Baltimore, MD 21205 USA
来源：
NATURE REVIEWS NEPHROLOGY | 2013年 / 9卷 / 07期
关键词：
HLA ANTIBODIES; REJECTION; RECIPIENTS; SURVIVAL;
D O I：
10.1038/nrneph.2013.84
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
O'Leary et al. report that the presence of anti-HLA antibodies at the time of simultaneous liver-kidney transplantation is associated with allograft dysfunction and shortened organ and patient survival. Preformed class I alloantibodies were eliminated after transplantation, whereas class II donor-specific antibodies persisted and were associated with poor outcomes.
引用
收藏
页码：373 / 374
页数：2
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