Sclerosing polycystic adenosis of parotid gland with dysplasia and ductal carcinoma in situ -: Report of three cases with immunohistochemical and ultrastructural examination

被引:45
|
作者
Skálová, A
Michal, M
Simpson, RHW
Stárek, I
Prádná, J
Pfaltz, M
机构
[1] Charles Univ, Fac Med, Dept Pathol, Plzen 30599, Czech Republic
[2] Royal Devon & Exeter Hosp, Dept Pathol, Exeter EX2 5DW, Devon, England
[3] Palacky Univ, Fac Med, Dept Otorhinolaryngol, CR-77147 Olomouc, Czech Republic
[4] Dist Hosp, Dept Pathol, Ceske Budejovice, Czech Republic
[5] Univ Zurich Hosp, Inst Clin Pathol, Zurich, Switzerland
关键词
salivary gland; sclerosing polycystic adenosis; sialadenopathy; dysplasia; ductal carcinoma in situ;
D O I
10.1007/s004280100481
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
We describe three cases of sclerosing polycystic adenosis (SPA) of the parotid gland, a salivary condition analogous to fibrocystic disease of the breast. For the first time, immunoreactivity for oestrogen and progesterone receptors was demonstrated, suggesting a possible participation of hormone stimulation in its pathogenesis. In addition, all our cases showed foci of dysplasia of the ductal epithelium, which in one case was severe enough to amount to carcinoma in situ. This feature that has not previously been reported in SPA.
引用
收藏
页码:29 / 35
页数:7
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