Rh(III)-Catalyzed C-H Amidation of Indoles with Isocyanates

被引：40

作者：

Jeong, Taejoo ^{[1
]}

Han, Sangil ^{[1
]}

Mishra, Neeraj Kumar ^{[1
]}

Sharma, Satyasheel ^{[1
]}

Lee, Seok-Yong ^{[1
]}

Oh, Joa Sub ^{[2
]}

Kwak, Jong Hwan ^{[1
]}

Jung, Young Hoon ^{[1
]}

Kim, In Su ^{[1
]}

机构：

[1] Sungkyunkwan Univ, Sch Pharm, Suwon 440746, South Korea

[2] Dankook Univ, Coll Pharm, Cheonan 330714, South Korea

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2015年 / 80卷 / 14期

基金：

新加坡国家研究基金会;

关键词：

NONREARRANGED MONOTERPENOID UNIT; CYCLIZATION DIRECT SYNTHESIS; RHENIUM-CATALYZED INSERTION; OXIDATIVE ORTHO-ACYLATION; O-METHYL OXIMES; BOND ACTIVATION; ARYL KETONES; INTRAMOLECULAR CYCLIZATION; DIRECT FUNCTIONALIZATION; UNSATURATED MOLECULES;

D O I：

10.1021/acs.joc.5b00763

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The rhodium(III)-catalyzed direct amidation of indoles and pyrroles with aryl and alkyl isocyanates is described. These transformations provide a facile and efficient construction of C-2-amidated N-heterocyclic scaffolds.

引用

页码：7243 / 7250

页数：8

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