Interstitial lung disease in connective tissue disorders

被引：338

作者：

Fischer, Aryeh ^{[2
]}

du Bois, Roland ^{[1
]}

机构：

[1] Univ London Imperial Coll Sci Technol & Med, London SW7 2AZ, England

[2] Natl Jewish Hlth, Div Rheumatol & Interstitial Lung Dis Program, Denver, CO USA

来源：

LANCET | 2012年 / 380卷 / 9842期

关键词：

IDIOPATHIC PULMONARY-FIBROSIS; COLLAGEN VASCULAR-DISEASE; PLACEBO-CONTROLLED TRIAL; SURFACTANT PROTEIN-D; SYSTEMIC-SCLEROSIS; RHEUMATOID-ARTHRITIS; MYCOPHENOLATE-MOFETIL; HISTOPATHOLOGIC SUBSETS; PROGNOSTIC-SIGNIFICANCE; BRONCHOALVEOLAR LAVAGE;

D O I：

10.1016/S0140-6736(12)61079-4

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Some of the most pressing challenges associated with interstitial lung disease (ILD) are how best to define, diagnose, and treat connective tissue disease-associated ILD (CTD-ILD)-disorders with potentially substantial morbidity and mortality. In this focused review, we address aspects of prognosis for CTD-ILD and what indices might predict outcome, together with lessons that can be learnt from clinical trials of systemic sclerosis-associated ILD and idiopathic pulmonary fibrosis and how these lessons might be applied to future studies of CTD-ILD.

引用

页码：689 / 698

页数：10

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