Intercalation and controlled release of pharmaceutically active compounds from a layered double hydroxide

被引：350

作者：

Khan, AI ^{[1
]}

Lei, LX ^{[1
]}

Norquist, AJ ^{[1
]}

O'Hare, D ^{[1
]}

机构：

[1] Univ Oxford, Inorgan Chem Lab, Oxford OX1 3QR, England

来源：

CHEMICAL COMMUNICATIONS | 2001年 / 22期

关键词：

D O I：

10.1039/b106465g

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A series of pharmaceutically active compounds including diclofenac, gemfibrozil, ibuprofen, naproxen, 2-propylpentanoic acid, 4-biphenylacetic acid and tolfenamic acid can be reversibly intercalated into a layered double hydroxide, initial studies suggest that these materials may have application as the basis of a novel tuneable drug delivery system.

引用

页码：2342 / 2343

页数：2

共 15 条

[1]

Choy J.H., 2000, MOL CRYST LIQ CRYS A, V341, P425

[2]

Choy JH, 2000, ANGEW CHEM INT EDIT, V39, P4042

[3] STRUCTURE-REACTIVITY RELATIONSHIPS FOR BASIC CATALYSTS DERIVED FROM A MG(2+)/AL(3+)/CO(3)(2-) LAYERED DOUBLE HYDROXIDE [J].