Channel-forming toxins: Tales of transformation

被引：142
作者：
Gouaux, E
机构：
[1] Dept. Biochem. and Molec. Biophys., Columbia Univ., 650 W. 168th Street, New York
来源：
CURRENT OPINION IN STRUCTURAL BIOLOGY | 1997年 / 7卷 / 04期
基金：
美国国家科学基金会; 美国国家卫生研究院;
关键词：
D O I：
10.1016/S0959-440X(97)80123-6
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Channel-forming bacterial toxins undergo a series of remarkable changes in solubility, oligomerization state, structure and dynamics during the processes of membrane binding, assembly, membrane insertion and channel formation. Recent high-resolution crystal structures of channel-forming toxins, in both water-soluble and membrane-bound, channel-formed slates, have brought a wealth of new information to bear on issues of structure, mechanism and function.
引用
收藏
页码：566 / 573
页数：8
相关论文
共 63 条
[1]   THE PRIMARY STRUCTURE OF CLOSTRIDIUM-SEPTICUM ALPHA-TOXIN EXHIBITS SIMILARITY WITH THAT OF AEROMONAS-HYDROPHILA AEROLYSIN [J].
BALLARD, J ;
CRABTREE, J ;
ROE, BA ;
TWETEN, RK .
INFECTION AND IMMUNITY, 1995, 63 (01) :340-344
[2]   COLICIN-A UNFOLDS DURING ITS TRANSLOCATION IN ESCHERICHIA-COLI-CELLS AND SPANS THE WHOLE CELL-ENVELOPE WHEN ITS PORE HAS FORMED [J].
BENEDETTI, H ;
LLOUBES, R ;
LAZDUNSKI, C ;
LETELLIER, L .
EMBO JOURNAL, 1992, 11 (02) :441-447
[3]   Staphylococcal alpha-toxin, streptolysin-O, and Escherichia coli hemolysin: Prototypes of pore-forming bacterial cytolysins [J].
Bhakdi, S ;
Bayley, H ;
Valeva, A ;
Walev, I ;
Walker, B ;
Weller, U ;
Kehoe, M ;
Palmer, M .
ARCHIVES OF MICROBIOLOGY, 1996, 165 (02) :73-79
[4]   ANTHRAX TOXIN - CHANNEL-FORMING ACTIVITY OF PROTECTIVE ANTIGEN IN PLANAR PHOSPHOLIPID-BILAYERS [J].
BLAUSTEIN, RO ;
KOEHLER, TM ;
COLLIER, RJ ;
FINKELSTEIN, A .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1989, 86 (07) :2209-2213
[5]   DIFFUSION LIMITATION IN THE BLOCK BY SYMMETRICAL TETRAALKYLAMMONIUM IONS OF ANTHRAX TOXIN CHANNELS IN PLANAR PHOSPHOLIPID-BILAYER MEMBRANES [J].
BLAUSTEIN, RO ;
FINKELSTEIN, A .
JOURNAL OF GENERAL PHYSIOLOGY, 1990, 96 (05) :943-957
[6]   THE CRYSTAL-STRUCTURE OF DIPHTHERIA-TOXIN [J].
CHOE, S ;
BENNETT, MJ ;
FUJII, G ;
CURMI, PMG ;
KANTARDJIEFF, KA ;
COLLIER, RJ ;
EISENBERG, D .
NATURE, 1992, 357 (6375) :216-222
[7]   STRUCTURE-FUNCTION OF THE CHANNEL-FORMING COLICINS [J].
CRAMER, WA ;
HEYMANN, JB ;
SCHENDEL, SL ;
DERIY, BN ;
COHEN, FS ;
ELKINS, PA ;
STAUFFACHER, CV .
ANNUAL REVIEW OF BIOPHYSICS AND BIOMOLECULAR STRUCTURE, 1995, 24 :611-641
[8]   THE PHOTOSYNTHETIC REACTION CENTER FROM THE PURPLE BACTERIUM RHODOPSEUDOMONAS-VIRIDIS [J].
DEISENHOFER, J ;
MICHEL, H .
SCIENCE, 1989, 245 (4925) :1463-1473
[9]   A mechanism for toxin insertion into membranes is suggested by the crystal structure of the channel-forming domain of colicin E1 [J].
Elkins, P ;
Bunker, A ;
Cramer, WA ;
Stauffacher, CV .
STRUCTURE, 1997, 5 (03) :443-458
[10]   BACILLUS-THURINGIENSIS CRYLA(A) INSECTICIDAL TOXIN - CRYSTAL-STRUCTURE AND CHANNEL FORMATION [J].
GROCHULSKI, P ;
MASSON, L ;
BORISOVA, S ;
PUSZTAICAREY, M ;
SCHWARTZ, JL ;
BROUSSEAU, R ;
CYGLER, M .
JOURNAL OF MOLECULAR BIOLOGY, 1995, 254 (03) :447-464
1234567