The diabetes epidemic: A national and global crisis

被引:72
作者
Bonow, RO [1 ]
Gheorghiade, M [1 ]
机构
[1] Northwestern Univ, Feinberg Sch Med, Div Cardiol, Chicago, IL 60611 USA
关键词
D O I
10.1016/j.amjmed.2003.10.014
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Diabetes mellitus is a serious problem that will soon reach epidemic proportions in the United States and throughout the world. The incidence of this condition will skyrocket in the next quarter century as demographic changes increase the size of highly susceptible populations (e.g., the elderly and Hispanic communities) and sociocultural developments create a more sedentary populace as well as expose people in developing nations to new risk factors for this. disease. Along with substantial direct morbidity and mortality, diabetes is independently associated with the incidence and severity of a variety of cardiovascular illnesses. Individuals with diabetes are substantially more likely than their nondiabetic counterparts to suffer stroke, myocardial infarction, or heart failure, with a worse prognosis following any of these conditions. Many factors may be relevant to this association, but recent studies have elucidated a major role for the metabolic syndrome, which has been shown to be predictive of both diabetes and cardiovascular disease. Consequently, early intervention to control blood glucose levels and other risk factors may mitigate the severity of these conditions, possibly even before the disease begins.
引用
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页码:2 / 10
页数:9
相关论文
共 52 条
[1]  
*AM DIAB ASS, 1998, DIABETES CARE, V21, P1551
[2]  
[Anonymous], PROJ TOT RES POP 5 Y, P2050
[3]  
[Anonymous], 2001, The world health report-mental health: New understanding, new hope
[4]  
[Anonymous], 1995, Diabetes in America
[5]  
Association AD, 2002, DIABETES CARE, V25, ps21, DOI [DOI 10.2337/DIACARE.25.2007.S21, 10.2337/diacare.25.2007.S21]
[6]   METABOLIC AND GENETIC-CHARACTERIZATION OF PREDIABETIC STATES - SEQUENCE OF EVENTS LEADING TO NON-INSULIN-DEPENDENT DIABETES-MELLITUS [J].
BECKNIELSEN, H ;
GROOP, LC .
JOURNAL OF CLINICAL INVESTIGATION, 1994, 94 (05) :1714-1721
[7]   INCIDENCE, PREVALENCE, AND MORTALITY OF DIABETES-MELLITUS IN WADENA, MARSHALL, AND GRAND-RAPIDS, MINNESOTA - THE 3-CITY STUDY [J].
BENDER, AP ;
SPRAFKA, JM ;
JAGGER, HG ;
MUCKALA, KH ;
MARTIN, CP ;
EDWARDS, TR .
DIABETES CARE, 1986, 9 (04) :343-350
[8]   World Heart Day 2002 - The international burden of cardiovascular disease: Responding to the emerging global epidemic [J].
Bonow, RO ;
Smaha, LA ;
Smith, SC ;
Mensah, GA ;
Lenfant, C .
CIRCULATION, 2002, 106 (13) :1602-1605
[9]  
BUTLER WJ, 1985, AM J EPIDEMIOL, V121, P541
[10]   Executive summary of the Third Report of the National Cholesterol Education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III) [J].
Cleeman, JI ;
Grundy, SM ;
Becker, D ;
Clark, LT ;
Cooper, RS ;
Denke, MA ;
Howard, WJ ;
Hunninghake, DB ;
Illingworth, DR ;
Luepker, RV ;
McBride, P ;
McKenney, JM ;
Pasternak, RC ;
Stone, NJ ;
Van Horn, L ;
Brewer, HB ;
Ernst, ND ;
Gordon, D ;
Levy, D ;
Rifkind, B ;
Rossouw, JE ;
Savage, P ;
Haffner, SM ;
Orloff, DG ;
Proschan, MA ;
Schwartz, JS ;
Sempos, CT ;
Shero, ST ;
Murray, EZ .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2001, 285 (19) :2486-2497