Simulation approaches to ion channel structure-function relationships

被引:184
作者
Tieleman, DP [1 ]
Biggin, PC [1 ]
Smith, GR [1 ]
Sansom, MSP [1 ]
机构
[1] Univ Oxford, Dept Biochem, Lab Mol Biophys, Oxford OX1 3QU, England
关键词
D O I
10.1017/S0033583501003729
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
引用
收藏
页码:473 / 561
页数:89
相关论文
共 323 条
[1]   The nicotinic acetylcholine receptor: from molecular model to single-channel conductance [J].
Adcock, C ;
Smith, GR ;
Sansom, MSP .
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS, 2000, 29 (01) :29-37
[2]   Electrostatics and the ion selectivity of ligand-gated channels [J].
Adcock, C ;
Smith, GR ;
Sansom, MSP .
BIOPHYSICAL JOURNAL, 1998, 75 (03) :1211-1222
[3]   SYNTHETIC PEPTIDES AS MODELS FOR ION CHANNEL PROTEINS [J].
AKERFELDT, KS ;
LEAR, JD ;
WASSERMAN, ZR ;
CHUNG, LA ;
DEGRADO, WF .
ACCOUNTS OF CHEMICAL RESEARCH, 1993, 26 (04) :191-197
[4]   PROTON CONDUCTANCE BY THE GRAMICIDIN WATER WIRE - MODEL FOR PROTON CONDUCTANCE IN THE F1F0 ATPASES [J].
AKESON, M ;
DEAMER, DW .
BIOPHYSICAL JOURNAL, 1991, 60 (01) :101-109
[5]   The effect of hydrophobic and hydrophilic channel walls on the structure and diffusion of water and ions [J].
Allen, TW ;
Kuyucak, S ;
Chung, SH .
JOURNAL OF CHEMICAL PHYSICS, 1999, 111 (17) :7985-7999
[6]   Molecular dynamics study of the KcsA potassium channel [J].
Allen, TW ;
Kuyucak, S ;
Chung, SH .
BIOPHYSICAL JOURNAL, 1999, 77 (05) :2502-2516
[7]   The potassium channel: Structure, selectivity and diffusion [J].
Allen, TW ;
Bliznyuk, A ;
Rendell, AP ;
Kuyucak, S ;
Chung, SH .
JOURNAL OF CHEMICAL PHYSICS, 2000, 112 (18) :8191-8204
[8]  
ANDERSEN OS, 1984, ANNU REV PHYSIOL, V46, P531
[9]  
[Anonymous], 1996, MOL MODELLING PRINCI
[10]   ENERGETICS OF ION PERMEATION THROUGH MEMBRANE CHANNELS - SOLVATION OF NA+ BY GRAMICIDIN-A [J].
AQVIST, J ;
WARSHEL, A .
BIOPHYSICAL JOURNAL, 1989, 56 (01) :171-182