In-Hospital Postoperative Pneumonia Following Geriatric Intertrochanteric Fracture Surgery: Incidence and Risk Factors

被引：35
作者：
Zhao, Kuo [1 ,2 ,3 ]
Zhang, Junzhe [1 ,2 ,3 ]
Li, Junyong [1 ,2 ,3 ]
Guo, Jialiang [1 ,2 ,3 ]
Meng, Hongyu [1 ,2 ,3 ]
Zhu, Yanbin [1 ,2 ,3 ]
Zhang, Yingze [1 ,2 ,3 ]
Hou, Zhiyong [1 ,2 ,3 ]
机构：
[1] Hebei Med Univ, Dept Orthopaed Surg, Hosp 3, Shijiazhuang 050051, Hebei, Peoples R China
[2] Key Lab Biomech Hebei Prov, Shijiazhuang 050051, Hebei, Peoples R China
[3] Orthopaed Res Inst Hebei Prov, Shijiazhuang 050051, Hebei, Peoples R China
来源：
CLINICAL INTERVENTIONS IN AGING | 2020年 / 15卷
关键词：
intertrochanteric fracture; postoperative pneumonia; in-hospital complication; geriatric population; risk factor; HIP FRACTURE; NATRIURETIC PEPTIDE; MORTALITY; COMPLICATIONS; ALBUMIN;
D O I：
10.2147/CIA.S268118
中图分类号：
R592 [老年病学]; C [社会科学总论];
学科分类号：
03 ; 0303 ; 100203 ;
摘要：
Purpose: The in-hospital death rate in cases of hip fracture ranges from 6% to 10%. Pneumonia is a serious complication for hip fracture patients that contributes to longer hospital stays and higher mortality rates; however, the prevalence and risk factors are not well established. To address this issue, the present study investigated the incidence of and risk factors for in-hospital postoperative pneumonia (IHPOP) following geriatric intertro-chanteric fracture surgery. Patients and Methods: Information on 1495 geriatric patients (>65 years) who underwent intertrochanteric fracture surgery at our hospital between October 2014 and December 2018 was extracted from a prospective hip fracture database and reviewed. Demographic informa-tion, clinical variables including surgical data, and preoperative laboratory indices that could potentially influence IHPOP were analyzed. Receiver operating characteristic curve analysis was performed and the optimum cutoff value for quantitative data was determined. Univariate and multivariate analyses were carried out to identify risk factors for IHPOP. Results: The incidence of IHPOP following geriatric intertrochanteric fracture surgery was 3.5% (53/1495 cases). The multivariate analysis showed that age 0.001), liver disease (OR=3.39, p=0.037), urinary tract infection (OR=8.46, p=0.005), creatine kinase (CK) MB 20 U/l (OR=2.31, p=0.020), B-type natriuretic peptide (BNP) >= 75 ng/l (OR=4.02, p=0.001), and D-dimer >2.26 mg/l (OR=2.69, p=0.002) were independent risks factor for the incidence of IHPOP following geriatric intertrochanteric fracture surgery. Conclusion: The incidence of IHPOP was 3.5% following geriatric intertrochanteric frac-ture surgery; age, male sex, chronic respiratory disease, liver disease, urinary tract infection, CKMB, BNP, and D-dimer were significant risk factors. Targeted preoperative management based on these factors could reduce the risk of IHPOP and mortality in these patients.
引用
收藏
页码：1599 / 1609
页数：11
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