Prostaglandin synthesis inhibitory activity in Zulu, Xhosa and Sotho medicinal plants

被引:0
|
作者
McGaw, LJ [1 ]
Jager, AK [1 ]
vanStaden, J [1 ]
机构
[1] UNIV NATAL,DEPT BOT,RES UNIT PLANT GROWTH & DEV,ZA-3209 SCOTTSVILLE,SOUTH AFRICA
关键词
antiinflammatory; cyclooxygenase; headache; medicinal plants; prostaglandin synthesis;
D O I
10.1002/(SICI)1099-1573(199703)11:2<113::AID-PTR27>3.0.CO;2-S
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Twenty-six plants used by Zulu healers for the treatment of pain and inflammation were assayed for cyclooxygenase inhibitory activity. The plant parts used by the traditional healers were dried and milled. Ethanol and aqueous extracts of the plants were prepared and assayed. Several plant extracts exhibited high inhibitory activity in the assay. Among these were Acacia rehmanniana, Cryptocarya latifolia, Dichrostachys cinerea, Erythrophleum lasianthum, Euclea natalensis, Felicia muricata, Mohria caffrorum, Phygelius capensis, Siphonochilus aethiopicus, Trichilia emetica and Turraea floribunda. The ethanol extracts generally showed higher activity than the aqueous extracts. (C) 1997 by John Wiley & Sons, Ltd.
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页码:113 / 117
页数:5
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