Inhalation glucocorticosteroid budesonide made in Russia: Effect on inflammation and bronchial hyperreactivity in long-term treatment of bronchial asthma

11 patients with severe bronchial asthma entered a randomized trial of glucocorticosteroid budesonide of Russian produce. Of them 6 patients received inhalations of budesonide (800 mu g/day for 6 months), 5 control patients did not receive the drug. As shown by investigations of external respiration and bronchoalveolar lavage with estimation of cytogram, metacholine provocative tests, fibrobronchoscopy budesonide inhalations relieved clinical symptoms of asthma, bronchial hyperreactivity and inflammation.