N-methyl-bacillithiol, a Novel Thiol from Anaerobic Bacteria

被引：4

作者：

Newton, Gerald L. ^{[1
]}

Rawat, Mamta ^{[2
]}

机构：

[1] Univ Calif San Diego, Div Biol Sci, San Diego, CA 92103 USA

[2] Calif State Univ Fresno, Dept Biol, Fresno, CA 93740 USA

来源：

MBIO | 2019年 / 10卷 / 01期

关键词：

Chlorobium; N-methyl-bacillithiol; anaerobes; bacillithiol; glutathione; thiols; GLUTATHIONE AMIDE; IDENTIFICATION; DETOXIFICATION; TRANSFERASE; METABOLISM; RESISTANCE; MYCOTHIOL;

D O I：

10.1128/mBio.02634-18

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

J. Hiras, S. V. Sharma, V. Raman, R. A. J. Tinson, et al. (mBio 9: e01603-18, 2018, https://doi.org/10.1128/mBio.01603-18) report on the identification of a novel thiol, N-methyl-bacillithiol (N-Me-BSH), in the green sulfur bacterium Chlorobium tepidum. In N-methyl-bacillithiol, the amine of the cysteine is methylated by a novel S-adenosylmethioneine transferase designated N-methyl-bacillithiol synthase A (NmbA). The Hiras et al. study is significant because it is the first report of the presence of N-Me-BSH in anaerobic bacteria.

引用

页数：5

共 50 条

[1] Differences in the availability of Hg-thiol complexes to anaerobic bacteria
Schaefer, J. K.
Rocks, S. S.
Morel, F. M. M.
GEOCHIMICA ET COSMOCHIMICA ACTA, 2010, 74 (12) : A917 - A917
[2] NOVEL ALKENYLETHER-LIPIDS FROM ANAEROBIC-BACTERIA
THIELE, OW
OULEVEY, J
BAHL, H
FETTE SEIFEN ANSTRICHMITTEL, 1985, 87 (14): : 551 - 556
[3] Thiol-Facilitated Cell Export and Desorption of Methylmercury by Anaerobic Bacteria
Lin, Hui
Lu, Xia
Liang, Liyuan
Gu, Baohua
ENVIRONMENTAL SCIENCE & TECHNOLOGY LETTERS, 2015, 2 (10): : 292 - 296
[4] Novel immobilisation supports for anaerobic bacteria
Armstrong, JL
Mavituna, F
Stephens, GM
1997 JUBILEE RESEARCH EVENT, VOLS 1 AND 2, 1997, : 969 - 972
[5] A NOVEL ANAEROBIC AMEBA WITH ENDOSYMBIOTIC BACTERIA
VANBRUGGEN, JJA
STUMM, CK
VOGELS, GD
ANTONIE VAN LEEUWENHOEK JOURNAL OF MICROBIOLOGY, 1985, 51 (5-6): : 578 - 579
[6] N-Methyl-2-Vinylpyridinium Ion As a Thiol Alkylator for Thiol Proteomics
Picklo, Matthew J.
Idso, Joseph
Jackson, Matthew I.
FREE RADICAL BIOLOGY AND MEDICINE, 2011, 51 : S22 - S22
[7] Chemical and Chemoenzymatic Syntheses of Bacillithiol: A Unique Low-Molecular-Weight Thiol amongst Low G+C Gram-Positive Bacteria
Sharma, Sunil V.
Jothivasan, Vishnu K.
Newton, Gerald L.
Upton, Heather
Wakabayashi, Judy I.
Kane, Melissa G.
Roberts, Alexandra A.
Rawat, Mamta
La Clair, James J.
Hamilton, Chris J.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2011, 50 (31) : 7101 - 7104
[8] RECOVERY OF ANAEROBIC BACTERIA FROM SWABS
COLLEE, JG
WATT, B
BROWN, R
JOHNSTONE, S
JOURNAL OF HYGIENE, 1974, 72 (03): : 339 - 347
[9] A biomimetic methyl transfer from amine to thiol
Tada, M
Kambe, T
Inouye, Y
CHEMICAL COMMUNICATIONS, 1998, (01) : 41 - 42
[10] A novel thermophilic anaerobic bacteria producing cyclodextrin glycosyltransferase
Avci, Ayse
Donmez, Sedat
PROCESS BIOCHEMISTRY, 2009, 44 (01) : 36 - 42

← 1 2 3 4 5 →