Significant enhancement of antitumor activity and bioavailability of intracellular pH-sensitive polymeric micelles by folate conjugation

被引：13

作者：

Bae, Y. ^{[1
]}

Kataoka, K. ^{[1
,2
]}

机构：

[1] Univ Tokyo, Div Clin Biotechnol, Ctr Dis Biol & Integrat Med, Grad Sch Med,Bunkyo Ku, Tokyo 1130033, Japan

[2] Univ Tokyo, Dept Mat Engn, Grad Sch Engn, Bunkyo Ku, Tokyo 1138656, Japan

来源：

JOURNAL OF CONTROLLED RELEASE | 2006年 / 116卷 / 02期

关键词：

D O I：

10.1016/j.jconrel.2006.09.044

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

027

引用

收藏

页码：E49 / E50

页数：3

相关论文

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[3] Preparation and biological characterization of polymeric micelle drug carriers with intracellular pH-triggered drug release property: Tumor permeability, controlled subcellular drug distribution, and enhanced in vivo antitumor efficacy
Bae, Y
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[J]. BIOCONJUGATE CHEMISTRY, 2005, 16 (01) : 122 - 130
[4] The dawning era of polymer therapeutics
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[J]. NATURE REVIEWS DRUG DISCOVERY, 2003, 2 (05) : 347 - 360
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