The biosynthesis of C5-C25 terpenoid compounds

被引:222
作者
Dewick, PM [1 ]
机构
[1] Univ Nottingham, Sch Pharmaceut Sci, Nottingham NG7 2RD, England
关键词
D O I
10.1039/b002685i
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
This review covers recently-published experimental information on the biosynthesis of terpenoids in the range C-5-C-25. In addition to sections on the mevalonate and mevalonate-independent (deoxyxylulose phosphate) pathways. the review considers in turn hemiterpenoids, polyprenyl diphosphate synthases, monoterpenoids, sesquiterpenoids, diterpenoids, and sesterterpenoids. The literature from January 1998 to December 2000 is reviewed, with 248 references cited.
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收藏
页码:181 / 222
页数:42
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共 254 条
[11]   The taxane diterpenoids [J].
Baloglu, E ;
Kingston, DGI .
JOURNAL OF NATURAL PRODUCTS, 1999, 62 (10) :1448-1472
[12]   Enzymatic synthesis of artemisinin from natural and synthetic precursors [J].
Bharel, S ;
Gulati, A ;
Abdin, MZ ;
Srivastava, PS ;
Vishwakarma, RA ;
Jain, SK .
JOURNAL OF NATURAL PRODUCTS, 1998, 61 (05) :633-636
[13]   Aminoethylcysteine can replace the function of the essential active site lysine of Pseudomonas mevalonii 3-hydroxy-3-methylglutaryl coenzyme A reductase [J].
Bochar, DA ;
Tabernero, L ;
Stauffacher, CV ;
Rodwell, VW .
BIOCHEMISTRY, 1999, 38 (28) :8879-8883
[14]   Sequence comparisons reveal two classes of 3-hydroxy-3-methylglutaryl coenzyme A reductase [J].
Bochar, DA ;
Stauffacher, CV ;
Rodwell, VW .
MOLECULAR GENETICS AND METABOLISM, 1999, 66 (02) :122-127
[15]   Investigation of the conserved lysines of Syrian hamster 3-hydroxy-3-methylglutaryl coenzyme A reductase [J].
Bochar, DA ;
Stauffacher, CV ;
Rodwell, VW .
BIOCHEMISTRY, 1999, 38 (48) :15848-15852
[16]   Terpenoid-based defenses in conifers:: cDNA cloning, characterization, and functional expression of wound-inducible (E)-α-bisabolene synthase from grand fir (Abies grandis) [J].
Bohlmann, J ;
Crock, J ;
Jetter, R ;
Croteau, R .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (12) :6756-6761
[17]   Terpenoid secondary metabolism in Arabidopsis thaliana:: cDNA cloning, characterization, and functional expression of a myrcene/(E)-β-ocimene synthase [J].
Bohlmann, J ;
Martin, D ;
Oldham, NJ ;
Gershenzon, J .
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 2000, 375 (02) :261-269
[18]   Plant terpenoid synthases: Molecular biology and phylogenetic analysis [J].
Bohlmann, J ;
Meyer-Gauen, G ;
Croteau, R .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (08) :4126-4133
[19]   cDNA cloning, characterization, and functional expression of four new monoterpene synthase members of the Tpsd gene family from grand fir (Abies grandis) [J].
Bohlmann, J ;
Phillips, M ;
Ramachandiran, V ;
Katoh, S ;
Croteau, R .
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1999, 368 (02) :232-243
[20]   Biosynthesis of C11 and C16 homoterpenes in higher plants;: Stereochemistry of the C-C-bond cleavage reaction [J].
Boland, W ;
Gäbler, A ;
Gilbert, M ;
Feng, ZF .
TETRAHEDRON, 1998, 54 (49) :14725-14736