Postoperative radiation performed at the same surgical facility associated with improved overall survival in oral cavity squamous cell carcinoma

被引：12

作者：

Amini, Arya ^{[1
,2
]}

Stokes, William A. ^{[1
]}

Jones, Bernard L. ^{[1
]}

Sampath, Sagus ^{[1
]}

Kang, Robert S. ^{[3
]}

Gernon, Thomas J. ^{[3
]}

Maghami, Ellie G. ^{[3
]}

Massarelli, Erminia ^{[4
]}

Bradley, Cathy J. ^{[5
]}

Karam, Sana D. ^{[2
]}

机构：

[1] City Hope Natl Canc Ctr, Dept Radiat Oncol, 1500 E Duarte Rd, Duarte, CA 91010 USA

[2] Univ Colorado, Sch Med, Dept Radiat Oncol, Aurora, CO USA

[3] City Hope Natl Canc Ctr, Div Head & Neck Surg, Duarte, CA USA

[4] City Hope Natl Canc Ctr, Dept Med Oncol & Therapeut Res, Duarte, CA USA

[5] Univ Colorado, Colorado Comprehens Canc Ctr, Dept Hlth Syst Management & Policy, Aurora, CO USA

来源：

HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK | 2019年 / 41卷 / 07期

关键词：

facility location; National Cancer Database (NCDB); oral cavity cancer; outcomes; postoperative radiation therapy (PORT); HEAD; VOLUME; THERAPY;

D O I：

10.1002/hed.25697

中图分类号：

R76 [耳鼻咽喉科学];

学科分类号：

100213 ;

摘要：

Background The purpose of this analysis is to evaluate whether postoperative radiotherapy (PORT) at the same facility as surgery portends to better survival outcomes compared to PORT given at a different facility. Methods Patients underwent upfront surgery at the National Cancer Database reporting facility followed by PORT. PORT was coded as performed at either the same facility or at a different facility as surgery. Results A total of 10 832 patients were selected. Five-year overall survival (OS) was higher in patients undergoing PORT at the same facility: 52.5% vs 48.4% (P < 0.001). PORT performed at the same facility was associated with improved OS under multivariate (HR, 0.92; P = 0.01) and propensity score matched (hazard ratio, 0.90; P = 0.004) analyses. Conclusions OS was better among patients with head and neck cancer who received PORT at the same facility as surgery.

引用

页码：2299 / 2308

页数：10

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