Risk factors for lymphatic and venous involvement in endoscopically resected gastric cancer

被引：32

作者：

Sekiguchi, Masau ^{[1
]}

Sekine, Shigeki ^{[2
]}

Oda, Ichiro ^{[1
]}

Nonaka, Satoru ^{[1
]}

Suzuki, Haruhisa ^{[1
]}

Yoshinaga, Shigetaka ^{[1
]}

Taniguchi, Hirokazu ^{[3
]}

Tsuda, Hitoshi ^{[3
]}

Kushima, Ryoji ^{[3
]}

Saito, Yutaka ^{[1
]}

机构：

[1] Natl Canc Ctr, Endoscopy Div, Tokyo, Japan

[2] Natl Canc Ctr, Mol Pathol Div, Chuo Ku, Tokyo 1040045, Japan

[3] Natl Canc Ctr, Div Pathol, Tokyo, Japan

来源：

JOURNAL OF GASTROENTEROLOGY | 2013年 / 48卷 / 06期

基金：

日本学术振兴会;

关键词：

Gastric cancer; Endoscopic resection; Papillary adenocarcinoma; Undifferentiated-type adenocarcinoma; Lymphatic involvement; Venous involvement; BLOOD-VESSEL INVASION; NODE METASTASIS; MONOCLONAL-ANTIBODY; PROGNOSTIC IMPACT; PREDICTORS; SURVIVAL; D2-40;

D O I：

10.1007/s00535-012-0696-7

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Lymphatic and venous involvement is a critical factor in the curability assessment of endoscopically resected gastric cancers; however, the risk factors for lymphatic and venous involvement in endoscopically resected gastric cancers remain unknown. To identify risk factors for lymphatic and venous involvement in endoscopically resected gastric cancers, we retrospectively reviewed a consecutive series of 1229 endoscopically resected gastric cancers in 1083 patients treated between January 2009 and December 2011. Lymphatic and venous involvement was detected in 57 (4.6 %) and 32 (2.6 %) lesions, respectively. A multivariate analysis identified a larger tumor size, deeper invasion (submucosal invasion or deeper), and the presence of a papillary or an undifferentiated-type adenocarcinoma component as independent risk factors for lymphatic involvement. As for venous involvement, deeper invasion (a parts per thousand yen500 mu m submucosal invasion), a macroscopically elevated type, and the presence of an undifferentiated-type adenocarcinoma component were identified as independent risk factors. The present study identified the independent risk factors for lymphatic and venous involvement in endoscopically resected gastric cancers. The recognition of these risk factors would help in the selection of lesions that may require a particularly careful histological evaluation.

引用

页码：706 / 712

页数：7

共 32 条

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