Altered lung antioxidant status in patients with mild asthma

被引：269

作者：

Kelly, FK ^{[1
]}

Mudway, J

Blomberg, A

Frew, A

Sandström, T

机构：

[1] Univ London Kings Coll, London SE1 7EH, England

[2] Univ Southampton, Univ Med, Air Pollut Grp, Southampton, Hants, England

[3] Univ Hosp, Dept Resp Med & Allergy, Umea, Sweden

来源：

LANCET | 1999年 / 354卷 / 9177期

基金：

英国惠康基金;

关键词：

D O I：

10.1016/S0140-6736(99)01812-7

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Lung lining fluid ascorbic acid (vitamin C) and alpha-tocopherol (vitamin E) concentrations are low in patients with mild asthma even though blood levels are normal or increased. These findings, along with the presence of increased amounts of oxidised glutathione in their airways, indicate that patients with asthma are subject to increased oxidative stress.

引用

页码：482 / 483

页数：2

共 4 条

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Blomberg, A
Frew, A
Holgate, ST
Sandstrom, T
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[3] *MIN AGR, 1990, HOUS FOOD CONS EXP
[4] PLASMA AND WHITE BLOOD-CELL ASCORBIC-ACID CONCENTRATIONS IN PATIENTS WITH BRONCHIAL-ASTHMA
OLUSI, SO
OJUTIKU, OO
JESSOP, WJE
IBOKO, MI
[J]. CLINICA CHIMICA ACTA, 1979, 92 (02) : 161 - 166

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