Finding their way: themes in germ cell migration

被引:43
作者
Barton, Lacy J.
LeBlanc, Michelle G.
Lehmann, Ruth [1 ]
机构
[1] NYU, Sch Med, HHMI, 540 First Ave, New York, NY 10016 USA
基金
美国国家卫生研究院;
关键词
MICRORNA-MEDIATED REGULATION; PROTEIN-COUPLED-RECEPTOR; TIME-LAPSE ANALYSIS; MESSENGER-RNA; TRANSEPITHELIAL MIGRATION; GONAD FORMATION; BETA-ARRESTIN; DEAD-END; DROSOPHILA; CHEMOKINE;
D O I
10.1016/j.ceb.2016.07.007
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Embryonic germ cell migration is a vital component of the germline lifecycle. The translocation of germ cells from the place of origin to the developing somatic gonad involves several processes including passive movements with underlying tissues, transepithelial migration, cell adhesion dynamics, the establishment of environmental guidance cues and the ability to sustain directed migration. How germ cells accomplish these feats in established model organisms will be discussed in this review, with a focus on recent discoveries and themes conserved across species.
引用
收藏
页码:128 / 137
页数:10
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