Finding their way: themes in germ cell migration

被引:43
作者
Barton, Lacy J.
LeBlanc, Michelle G.
Lehmann, Ruth [1 ]
机构
[1] NYU, Sch Med, HHMI, 540 First Ave, New York, NY 10016 USA
基金
美国国家卫生研究院;
关键词
MICRORNA-MEDIATED REGULATION; PROTEIN-COUPLED-RECEPTOR; TIME-LAPSE ANALYSIS; MESSENGER-RNA; TRANSEPITHELIAL MIGRATION; GONAD FORMATION; BETA-ARRESTIN; DEAD-END; DROSOPHILA; CHEMOKINE;
D O I
10.1016/j.ceb.2016.07.007
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Embryonic germ cell migration is a vital component of the germline lifecycle. The translocation of germ cells from the place of origin to the developing somatic gonad involves several processes including passive movements with underlying tissues, transepithelial migration, cell adhesion dynamics, the establishment of environmental guidance cues and the ability to sustain directed migration. How germ cells accomplish these feats in established model organisms will be discussed in this review, with a focus on recent discoveries and themes conserved across species.
引用
收藏
页码:128 / 137
页数:10
相关论文
共 105 条
  • [1] The onset of germ cell migration in the mouse embryo
    Anderson, R
    Copeland, TK
    Schöler, H
    Heasman, J
    Wylie, C
    [J]. MECHANISMS OF DEVELOPMENT, 2000, 91 (1-2) : 61 - 68
  • [2] Impaired colonization of the gonads by primordial germ cells in mice lacking a chemokine, stromal cell-derived factor-1 (SDF-1)
    Ara, T
    Nakamura, Y
    Egawa, T
    Sugiyama, T
    Abe, K
    Kishimoto, T
    Matsui, Y
    Nagasawa, T
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2003, 100 (09) : 5319 - 5323
  • [3] Reduction in E-cadherin expression fosters migration of Xenopus laevis primordial germ cells
    Baronsky, Thilo
    Dzementsei, Aliaksandr
    Oelkers, Marieelen
    Melchert, Juliane
    Pieler, Tomas
    Janshoff, Andreas
    [J]. INTEGRATIVE BIOLOGY, 2016, 8 (03) : 349 - 358
  • [4] The origin and migration of primordial germ cells in the mouse
    Bendel-Stenzel, M
    Anderson, R
    Heasman, J
    Wylie, C
    [J]. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY, 1998, 9 (04) : 393 - 400
  • [5] The role of cadherins during primordial germ cell migration and early gonad formation in the mouse
    Bendel-Stenzel, MR
    Gomperts, M
    Anderson, R
    Heasman, J
    Wylie, C
    [J]. MECHANISMS OF DEVELOPMENT, 2000, 91 (1-2) : 143 - 152
  • [6] Transition from non-motile behaviour to directed migration during early PGC development in zebrafish
    Blaser, H
    Eisenbeiss, S
    Neuman, M
    Reichman-Fried, M
    Thisse, B
    Thisse, C
    Raz, E
    [J]. JOURNAL OF CELL SCIENCE, 2005, 118 (17) : 4027 - 4038
  • [7] Control of chemokine-guided cell migration by ligand sequestration
    Boldajipour, Bijan
    Mahabaleshwar, Harsha
    Kardash, Elena
    Reichman-Fried, Michal
    Blaser, Heiko
    Minina, Sofia
    Wilson, Duncan
    Xu, Qiling
    Raz, Erez
    [J]. CELL, 2008, 132 (03) : 463 - 473
  • [8] Boyle M, 1997, DEVELOPMENT, V124, P971
  • [9] Caussinus E, 2013, CURR PROTOC PROTEIN, V73
  • [10] Loss of Wnt5a Disrupts Primordial Germ Cell Migration and Male Sexual Development in Mice
    Chawengsaksophak, Kallayanee
    Svingen, Terje
    Ng, Ee Ting
    Epp, Trevor
    Spiller, Cassy M.
    Clark, Charlotte
    Cooper, Helen
    Koopman, Peter
    [J]. BIOLOGY OF REPRODUCTION, 2012, 86 (01)