An Efficient and Straightforward Method to New Organic Compounds: Homodrimane Sesquiterpenoids with Diazine Units

被引：16

作者：

Kuchkova, Kaleria ^{[1
]}

Aricu, Aculina ^{[1
]}

Barba, Alic ^{[1
]}

Vlad, Pavel ^{[1
]}

Shova, Sergiu ^{[2
]}

Secara, Elena ^{[1
]}

Ungur, Nicon ^{[1
]}

Zbancioc, Gheorghita ^{[3
]}

Mangalagiu, Ionel I. ^{[3
]}

机构：

[1] Moldavian Acad Sci, Inst Chem, Acad 3, Kishinev 2028, Moldova

[2] Petru Poni Inst Macromol Chem, Iasi 700487, Romania

[3] Alexandru Ioan Cuza Univ, Organ & Biochem Dept, Iasi 700506, Romania

来源：

SYNLETT | 2013年 / 24卷 / 06期

关键词：

homodrimane; sesquiterpenoids; diazine; one-pot bisacylation; bisacylamide; CONTAINING DRIMANE SESQUITERPENOIDS; (-)-AMBROX(R); CHEMISTRY;

D O I：

10.1055/s-0032-1318253

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A comprehensive study of the synthesis and structure of new homodrimane sesquiterpenoids with diazine skeleton is presented. This is the first synthesis of homodrimane sesquiterpenoids with diazine skeleton. In the same time, an efficient way for the one-pot bisacylation of 2-aminopyrimidine is reported. The structure of the bisacylamide was proven unambiguously, including the single-crystal X-ray structure determination. A reliable explication and feasible reaction mechanisms for the obtained compounds are presented.

引用

页码：697 / 700

页数：4

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