Patent Foramen Ovale

被引：9
作者：
Dattilo, Philip B. [1 ]
Kim, Michael S. [2 ]
Carroll, John D. [1 ]
机构：
[1] Univ Colorado Denver, Div Cardiol, Aurora, CO 80045 USA
[2] Univ Colorado Denver, Struct Heart Dis Program, Div Cardiol, Aurora, CO 80045 USA
来源：
CARDIOLOGY CLINICS | 2013年 / 31卷 / 03期
关键词：
Patent foramen ovale; Cryptogenic stroke; Migraine; Transcatheter closure; MIST; CLOSURE I; RESPECT; PC Trial; ATRIAL SEPTAL-DEFECT; RECURRENT NEUROLOGICAL EVENTS; INTERMEDIATE-TERM RISK; TRANSCATHETER CLOSURE; PERCUTANEOUS CLOSURE; CRYPTOGENIC STROKE; MEDICAL THERAPY; PARADOXICAL EMBOLISM; MULTICENTER; OCCLUDER;
D O I：
10.1016/j.ccl.2013.05.002
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Patent foramen ovale (PFO) is a common developmental anomaly that allows for the passage of blood and other substances from the venous to the arterial circulation. The study of PFO closure has been challenging due to widely available off-label closures performed outside the clinical trial setting. To date, no study has demonstrated benefit of closure using intention-to-treat analyses. Secondary and subpopulation analyses suggest that there is benefit to closure in patients with atrial septal aneurysms and/or substantial degrees of right-to-left shunting. This article reviews the history, associated technologies, and current data regarding PFO closure.
引用
收藏
页码：401 / +
页数：16
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