What hematological and endocrinal indicators are important in COVID-19 infection?

被引：0

作者：

Ostadrahimi, Alireza ^{[1
]}

Sadra, Vahideh ^{[2
]}

Bahrami, Amir ^{[2
]}

Razzaghi, Zohreh ^{[2
]}

Najafipour, Mostafa ^{[3
]}

Tutunchi, Helda ^{[2
]}

Najafipour, Farzad ^{[2
]}

机构：

[1] Tabriz Univ Med Sci, Sch Nutr & Food Sci, Dept Clin Nutr, Nutr Res Ctr, Tabriz, Iran

[2] Tabriz Univ Med Sci, Endocrine Res Ctr, Tabriz, Iran

[3] Ardabil Azad Univ Med Sci, Dept Internal Med, Fac Med, Ardebil, Iran

来源：

HEALTH PROMOTION PERSPECTIVES | 2022年 / 12卷 / 02期

关键词：

Coronavirus; Endocrine system; Hematology; Triiodothyronine; Free vitamin D; DISEASE; 2019; COVID-19; HOSPITALIZED-PATIENTS; CORONAVIRUS; LEUKOCYTOSIS; LYMPHOPENIA;

D O I：

10.34172/hpp.2022.26

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Background: Clinical evidence of endocrine involvement in coronavirus disease needs further investigation. The aim of the present study was to assess the relationship between hematology and endocrine parameters in coronavirus disease 2019 (COVID-19) infection. Methods: In the present cross-sectional study, a total of 320 patients (215 survivors and 105 non-survivors) with confirmed COVID-19 infection were enrolled. After isolation of serum samples, hematological, biochemical, and hormonal parameters were analyzed. Results: The mean age of survivors and non-survivors was 58.92 (SD: 15.28) and 63.65 (SD: 16.62) years, respectively. The results demonstrated significant differences in free triiodothyronine (FT3) [MD (95% CI): 0.40 (0.10, 0.71), P = 0.009], total calcium [MD (95% CI): 0.53 (0.21, 0.86), P = 0.003], vitamin D [MD (95% CI): 7.72 (6.38, 9.05), P = 0.003], erythrocyte sedimentation rate (ESR) [MD (95% CI): 17.09 (9.38, 22.05), P = 0.004) and serum ferritin [Median difference: -1091.9, P<0.001), between survivors and non-survivors, respectively. Conclusion: The results revealed that some hematological and endocrine factors play an important role in prognosis of COVID-19 infection. However, further studies with a larger population are required to clarify the exact effects of COVID-19 on the endocrine system.

引用

页码：212 / 217

页数：6

共 37 条

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