The antidepressant mechanism of action of vagus nerve stimulation: Evidence from preclinical studies

被引：59

作者：

Grimonprez, Annelies ^{[1
]}

Raedt, Robrecht ^{[1
]}

Baeken, Chris ^{[2
,3
]}

Boon, Paul ^{[1
]}

Vonck, Kristl ^{[1
]}

机构：

[1] Univ Ghent, LCEN3, Dept Neurol, Inst Neurosci, B-9000 Ghent, Belgium

[2] Univ Ghent, Dept Psychiat & Med Psychol, B-9000 Ghent, Belgium

[3] Vrije Univ Brussel, UZ Brussel, Dept Psychiat, Brussels, Belgium

来源：

NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS | 2015年 / 56卷

关键词：

Vagus nerve stimulation; Major depressive disorder; The monoaminergic hypothesis of major; depressive disorder; The neural plasticity hypothesis of major; TREATMENT-RESISTANT DEPRESSION; NUCLEUS-TRACTUS-SOLITARIUS; CHRONIC MILD STRESS; NEUROTROPHIC FACTOR BDNF; FIBROBLAST-GROWTH-FACTOR; LOCUS-COERULEUS; HIPPOCAMPAL NEUROGENESIS; RAT-BRAIN; ADULT-RAT; TRYPTOPHAN DEPLETION;

D O I：

10.1016/j.neubiorev.2015.06.019

中图分类号：

B84 [心理学]; C [社会科学总论]; Q98 [人类学];

学科分类号：

03 ; 0303 ; 030303 ; 04 ; 0402 ;

摘要：

Vagus nerve stimulation (VNS) is a proposed neuromodulatory treatment for medically refractory major depression. Although VNS is already used in clinical practice, the underlying mechanism of action remains unknown. The present review provides an overview of the preclinical VNS studies in view of two major hypotheses in depression research: the monoaminergic and the neural plasticity hypothesis of depression. (C) 2015 Elsevier Ltd. All rights reserved.

引用

页码：26 / 34

页数：9

共 131 条

[1] Vagus Nerve Stimulation Therapy Randomized to Different Amounts of Electrical Charge for Treatment-Resistant Depression: Acute and Chronic Effects [J].

Aaronson, Scott T. ;

Carpenter, Linda L. ;

Conway, Charles R. ;

Reimherr, Frederick W. ;

Lisanby, Sarah H. ;

Schwartz, Thomas L. ;

Moreno, Francisco A. ;

Dunner, David L. ;

Lesem, Michael D. ;

Thompson, Peter M. ;

Husain, Mustafa ;

Vine, Craig J. ;

Banov, Michael D. ;

Bernstein, Lawrence P. ;

Lehman, Robert B. ;

Brannon, Guy E. ;

Keepers, George A. ;

O'Reardon, John P. ;

Rudolph, Richard L. ;

Bunker, Mark .

BRAIN STIMULATION, 2013, 6 (04) :631-640

[2]

Alonso J, 2004, ACTA PSYCHIAT SCAND, V109, P21

[3] NUCLEUS-TRACTUS-SOLITARIUS - GATEWAY TO NEURAL CIRCULATORY CONTROL [J].

ANDRESEN, MC ;

KUNZE, DL .

ANNUAL REVIEW OF PHYSIOLOGY, 1994, 56 :93-116

[4]

[Anonymous], J PSYCHIAT IN PRESS

[5]

[Anonymous], BRAIN STIMU IN PRESS

[6] Numerous GABAergic aferents to locus ceruleus in the pericerulear dendritic zone: Possible interneuronal pool [J].

Aston-Jones, G ;

Zhu, Y ;

Card, JP .

JOURNAL OF NEUROSCIENCE, 2004, 24 (09) :2313-2321

[7]

ASTONJONES G, 1991, PROG BRAIN RES, V88, P47

[8] Two-Year Outcome of Vagus Nerve Stimulation in Treatment-Resistant Depression [J].

Bajbouj, Malek ;

Merkl, Angela ;

Schlaepfer, Thomas E. ;

Frick, Caroline ;

Zobel, Astrid ;

Maier, Wolfgang ;

O'Keane, Veronica ;

Corcoran, Ciaran ;

Adolfsson, Rolf ;

Trimble, Michael ;

Rau, Harald ;

Hoff, Hans-Joachim ;

Padberg, Frank ;

Mueller-Siecheneder, Florian ;

Audenaert, Kurt ;

van den Abbeele, Dirk ;

Matthews, Keith ;

Christmas, David ;

Eljamel, Sam ;

Heuser, Isabella .

JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY, 2010, 30 (03) :273-281

[9] SUPPRESSION OF FIRING ACTIVITY OF 5-HT NEURONS IN THE DORSAL RAPHE BY ALPHA-ADRENOCEPTOR ANTAGONISTS [J].

BARABAN, JM ;

AGHAJANIAN, GK .

NEUROPHARMACOLOGY, 1980, 19 (04) :355-363

[10] Depression: from psychopathology to pathophysiology [J].

Belzung, Catherine ;

Willner, Paul ;

Philippot, Pierre .

CURRENT OPINION IN NEUROBIOLOGY, 2015, 30 :24-30

← 1 2 3 4 5 6 7 8 9 10 →