Protein kinase inhibitors: breakthrough medicines and the next generation

被引：8
作者：
Sawyer, Tomi K. [1 ]
Wu, Joe C. [2 ]
Sawyer, Jonathon R. [3 ]
English, Jessie M. [4 ]
机构：
[1] Aileron Therapeut, Cambridge, MA 02139 USA
[2] GlaxoSmithKline PLC, Cambridge, MA 02139 USA
[3] Providence Coll, Providence, RI 02908 USA
[4] Dana Farber Canc Inst, Belfer Inst Appl Canc Sci, Boston, MA 02115 USA
来源：
EXPERT OPINION ON INVESTIGATIONAL DRUGS | 2013年 / 22卷 / 06期
关键词：
kinase inhibitor; protein kinase; proteins; small-molecule; IMATINIB; THERAPY;
D O I：
10.1517/13543784.2013.804509
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
In this issue of Expert Opinion on Investigational Drugs, several protein kinases families and pathways underlying cancer and other diseases are reviewed and several small molecule inhibitors that are in clinical trials are further described. Highlights of these reviews and drug evaluations are summarized in this editorial.
引用
收藏
页码：675 / 678
页数：4
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