On the complexity of unsigned translocation distance

被引:21
作者
Zhu, DM
Wang, LS [1 ]
机构
[1] City Univ Hong Kong, Dept Comp Sci, Kowloon, Hong Kong, Peoples R China
[2] Shandong Univ, Sch Comp Sci & Technol, Jinan 250100, Peoples R China
基金
中国国家自然科学基金;
关键词
unsigned translocation; NP-hardness; inapproximability;
D O I
10.1016/j.tcs.2005.09.078
中图分类号
TP301 [理论、方法];
学科分类号
081202 ;
摘要
Translocation is one of the basic operations for genome rearrangement. Translocation distance is the minimum number of translocations required to transform one genome into the other. In this paper, we show that computing the translocation distance for unsigned genomes is NP-hard. Moreover, we show that approximating the translocation distance for unsigned genomes within ratio 1.00017 is NP-hard. (c) 2005 Elsevier B.V. All rights reserved.
引用
收藏
页码:322 / 328
页数:7
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