Osmotic stress responses of Streptococcus mutans UA159

被引:20
|
作者
Abranches, J [1 ]
Lemos, JA [1 ]
Burne, RA [1 ]
机构
[1] Univ Florida, Dept Oral Biol, Coll Dent, Gainesville, FL 32610 USA
关键词
osmotic stress response; gene regulation; transport; caries; biofilm; Streptococcus mutans;
D O I
10.1111/j.1574-6968.2005.00076.x
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
The hyperosmotic stress response of Streptococcus mutans was investigated. Real-time reverse transcriptase-PCR and slot-blot analysis revealed that opuAA, opcA, Smu.2115, sodA and nox were induced after exposure to 0.4 M NaCl. Our data suggest that there is a cross-talk between osmotic and oxidative stress responses in S. mutans. Inactivation of Smu.2115, encoding a putative oxidoreductase, resulted in an acid-resistant and hydrogen peroxide-sensitive phenotype.
引用
收藏
页码:240 / 246
页数:7
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