Osmotic stress responses of Streptococcus mutans UA159

被引：21
作者：
Abranches, J [1 ]
Lemos, JA [1 ]
Burne, RA [1 ]
机构：
[1] Univ Florida, Dept Oral Biol, Coll Dent, Gainesville, FL 32610 USA
来源：
FEMS MICROBIOLOGY LETTERS | 2006年 / 255卷 / 02期
关键词：
osmotic stress response; gene regulation; transport; caries; biofilm; Streptococcus mutans;
D O I：
10.1111/j.1574-6968.2005.00076.x
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
The hyperosmotic stress response of Streptococcus mutans was investigated. Real-time reverse transcriptase-PCR and slot-blot analysis revealed that opuAA, opcA, Smu.2115, sodA and nox were induced after exposure to 0.4 M NaCl. Our data suggest that there is a cross-talk between osmotic and oxidative stress responses in S. mutans. Inactivation of Smu.2115, encoding a putative oxidoreductase, resulted in an acid-resistant and hydrogen peroxide-sensitive phenotype.
引用
收藏
页码：240 / 246
页数：7
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